Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 21179020
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Histone~SIR2, Histone_H2A_C~SIR2
Common GO terms GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0031507 - heterochromatin formation
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 132
Sc

1 562
+ Sc
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Service provided by Combinatics, Japan

Last updated: 11Aug2025