HitPredict

Interactor 1: LDHB (P07195)
L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46)
Gene: LDHB

Interactor 2: LDHB (P07195)
L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46)
Gene: LDHB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 25416956, 32296183, 11276087, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, x-ray crystallography, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ldh_1_C~Ldh_1_C, Ldh_1_C~Ldh_1_N, Ldh_1_N~Ldh_1_N
Common GO terms GO:0004459 - L-lactate dehydrogenase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005829 - cytosol
and 9 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 334
Hs

1 334
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+ Cj

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Last updated: 15 Jul 2024