HitPredict

Interactor 1: SYEP (P07814)
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]
Gene: EPRS1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	17400507, unassigned1853
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0042803 - protein homodimerization activity and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1512 Hs			1 2527
+	Hs
		814467 SYQ_HUMAN (159-704): 0: 631: 31.19		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		643757 SYTC_HUMAN (703-1410): 0: 573: 15.62		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130541 SYTM_HUMAN (774-1411): 7.77e-150: 476: 14.87		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1126900 SYEM_HUMAN (198-487): 4.99e-64: 229: 21.75		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		616059 SYWC_HUMAN (751-804): 5.49e-09: 62.4: 51.72		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		201180 SYEP_HUMAN (1-1512): 0: 1810: 100.00		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201224 SYTC_HUMAN (703-1410): 0: 573: 15.62		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83