HitPredict

Interactor 1: HEPS (P05981)
Serine protease hepsin (EC 3.4.21.106) (Transmembrane protease serine 1) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]
Gene: HPN

Interactor 2: TOR2A (Q5JU69)
Torsin-2A (Torsin family 2 member A) (Torsin-related protein 1)
Gene: TOR2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 321
+	Hs
		160795 HEPS_HUMAN (1-417): 5.68e-177: 501: 100.00		TOR1B_HUMAN (8-320): 9.37e-126: 364: 43.13
+	Hs
		160675 HEPS_HUMAN (1-417): 5.68e-177: 501: 100.00		TOR1A_HUMAN (6-320): 1.48e-124: 361: 41.59
+	Hs
		437793 HEPS_HUMAN (1-417): 5.68e-177: 501: 100.00		TOR3A_HUMAN (10-321): 1.29e-108: 323: 36.59
+	Hs
		160758 TMPSD_HUMAN (36-411): 8.52e-125: 375: 34.92		TOR1A_HUMAN (6-320): 1.48e-124: 361: 41.59
+	Hs
		437733 HEPS_HUMAN (1-417): 5.68e-177: 501: 100.00		TOR2X_HUMAN (1-197): 4.46e-71: 222: 100.00
+	Hs
		944929 TMPS3_HUMAN (44-406): 5.6e-131: 386: 37.43		TOR3A_HUMAN (10-321): 1.29e-108: 323: 36.59
+	Hs
		1432877 TMPS5_HUMAN (11-403): 3.19e-129: 382: 33.08		TOR3A_HUMAN (10-321): 1.29e-108: 323: 36.59
+	Hs
		1418345 TMPSD_HUMAN (36-411): 8.52e-125: 375: 34.92		TOR3A_HUMAN (10-321): 1.29e-108: 323: 36.59
+	Hs
		398009 KLKB1_HUMAN (76-416): 1.75e-96: 303: 31.14		TOR3A_HUMAN (10-321): 1.29e-108: 323: 36.59
+	Hs
		786278 TMPS4_HUMAN (13-406): 1.34e-123: 367: 32.49		LONM_HUMAN (1-320): 2.43e-68: 231: 13.53
+	Hs
		188826 TMPS2_HUMAN (13-406): 1.03e-121: 363: 31.23		LONM_HUMAN (1-320): 2.43e-68: 231: 13.53
+	Hs
		160782 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		TOR1A_HUMAN (6-320): 1.48e-124: 361: 41.59
+	Hs
		786157 TM11B_HUMAN (153-403): 1.2e-101: 310: 40.00		LONM_HUMAN (1-320): 2.43e-68: 231: 13.53
+	Hs
		1207203 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		TOR2A_HUMAN (1-321): 6.18e-120: 349: 100.00
+	Hs
		1433305 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		TOR3A_HUMAN (10-321): 1.29e-108: 323: 36.59
+	Hs
		1324238 ST14_HUMAN (152-400): 2.46e-50: 183: 40.70		TOR2X_HUMAN (1-197): 4.46e-71: 222: 100.00