Protein: KLKB1
Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) (PKK) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain]

Gene: KLKB1
Organism: Homo sapiens
Interactions: 21
UniProt ID: P03952

Gene Ontology (top 5):
GO:0002542 - Factor XII activation
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

370388

KNG1
Kininogen-1

5

1

Small-scale

0.712

High

398001

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

13

High-throughput

0.691

High

398002

NID2
Nidogen-2

1

6

High-throughput

0.691

High

398000

IPSP
Plasma serine protease inhibitor

1

11

Small-scale

0.647

High

398010

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

2

0

High-throughput

0.602

High

398009

TOR3A
Torsin-3A

1

14

High-throughput

0.536

High

217692

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.515

High

398008

Q8TAS3
PRRG2 protein

1

4

High-throughput

0.515

High

398004

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

398011

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.513

High

143782

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

2

High-throughput

0.470

High

162431

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.470

High

398005

SLN12
Ribonuclease SLFN12

1

1

High-throughput

0.470

High

398006

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

2

High-throughput

0.470

High

398013

SNX12
Sorting nexin-12

1

2

High-throughput

0.470

High

398003

CND2
Condensin complex subunit 2

2

0

High-throughput

0.328

High

398014

ZBTB1
Zinc finger and BTB domain-containing protein 1

2

0

High-throughput

0.328

High

91518

C9J082
Nephrocystin 1

1

0

High-throughput

0.268

Low

128368

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.268

Low

398007

T185A
Transmembrane protein 185A

1

0

High-throughput

0.268

Low

398012

EI2BD
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025