HitPredict

Interactor 1: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Interactor 2: KRT82 (Q9NSB4)
Keratin, type II cuticular Hb2 (Keratin-82) (K82) (Type II hair keratin Hb2) (Type-II keratin Kb22)
Gene: KRT82

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0031424 - keratinization GO:0045095 - keratin filament GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 473 Hs			1 513
+	Hs
		380539 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C1_HUMAN (88-445): 2.83e-131: 397: 56.79
+	Hs
		444997 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C3_HUMAN (92-431): 1.87e-131: 397: 58.72
+	Hs
		408981 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C8_HUMAN (40-460): 4.78e-111: 339: 51.65
+	Hs
		445029 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		KRT85_HUMAN (1-487): 5.67e-103: 319: 60.12
+	Hs
		445028 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		KRT83_HUMAN (1-470): 3.67e-101: 314: 58.17
+	Hs
		445046 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		KRT81_HUMAN (7-511): 5.11e-100: 312: 56.14
+	Hs
		213927 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		KRT86_HUMAN (7-496): 1.35e-98: 307: 56.88
+	Hs
		445082 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C73_HUMAN (1-512): 1.64e-95: 301: 42.19
+	Hs
		213930 K1C15_HUMAN (116-429): 2.97e-155: 450: 76.19		KRT86_HUMAN (7-496): 1.35e-98: 307: 56.88
+	Hs
		318770 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C75_HUMAN (1-511): 2.71e-89: 285: 45.19
+	Hs
		445061 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C71_HUMAN (1-512): 7.27e-85: 273: 42.94
+	Hs
		445068 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C79_HUMAN (14-507): 2.18e-84: 272: 42.86
+	Hs
		318776 K1C15_HUMAN (116-429): 2.97e-155: 450: 76.19		K2C75_HUMAN (1-511): 2.71e-89: 285: 45.19
+	Hs
		445048 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C72_HUMAN (4-512): 8.38e-83: 267: 42.86
+	Hs
		445000 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C5_HUMAN (1-434): 8.54e-77: 254: 48.76
+	Hs
		380438 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C6B_HUMAN (85-434): 2.39e-76: 252: 59.09
+	Hs
		445017 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C6C_HUMAN (85-434): 4.64e-76: 251: 59.38
+	Hs
		359454 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C6A_HUMAN (85-434): 2.33e-75: 249: 59.94
+	Hs
		445078 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C74_HUMAN (7-502): 2.44e-73: 243: 41.57
+	Hs
		445002 K1C16_HUMAN (1-461): 1.58e-161: 467: 100.00		K2C4_HUMAN (7-438): 1.31e-68: 230: 45.60