HitPredict

Interactor 1: S10A4 (P26447)
Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)
Gene: S100A4

Interactor 2: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	S_100~S_100
Common GO terms	GO:0005509 - calcium ion binding GO:0046914 - transition metal ion binding GO:0048306 - calcium-dependent protein binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 101 Hs			1 98
+	Hs
		1214472 Q5T7Y6_HUMAN (1-90): 3.21e-40: 131: 51.11		Q5T7Y6_HUMAN (2-91): 3.16e-40: 131: 52.22
+	Mm
		450157 S10A4_MOUSE (1-101): 8.8e-41: 131: 93.07		S10A4_MOUSE (2-97): 3.81e-39: 127: 61.46
+	Mm
		450158 S10A4_MOUSE (1-101): 8.8e-41: 131: 93.07		S10A1_MOUSE (2-91): 2.65e-37: 122: 51.11
+	Hs
		657021 S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00		S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22
+	Hs
		686779 S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00		S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46
+	Hs
		657022 S10A1_HUMAN (1-90): 8.22e-38: 123: 51.11		S10A2_HUMAN (1-98): 3.29e-39: 127: 100.00
+	Hs
		682510 Q5T7Y6_HUMAN (1-90): 3.21e-40: 131: 51.11		S100P_HUMAN (4-92): 1.21e-35: 118: 42.70
+	Hs
		657018 S10A1_HUMAN (1-90): 8.22e-38: 123: 51.11		S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22
+	Hs
		731754 S10AB_HUMAN (2-97): 1.43e-37: 123: 27.84		S10AB_HUMAN (2-97): 2.19e-37: 123: 29.90
+	Hs
		657024 S10A1_HUMAN (1-90): 8.22e-38: 123: 51.11		S10A3_HUMAN (2-98): 2.61e-36: 120: 43.30
+	Hs
		407637 Q5T7Y6_HUMAN (1-90): 3.21e-40: 131: 51.11		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		657019 S10A1_HUMAN (1-90): 8.22e-38: 123: 51.11		S100P_HUMAN (4-92): 1.21e-35: 118: 42.70
+	Hs
		407583 S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		657041 S10A1_HUMAN (1-90): 8.22e-38: 123: 51.11		S100Z_HUMAN (2-91): 3.93e-34: 114: 43.33
+	Hs
		407580 S10A1_HUMAN (1-90): 8.22e-38: 123: 51.11		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		407589 S10AB_HUMAN (2-97): 1.43e-37: 123: 27.84		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		445129 S10A4_HUMAN (1-101): 5.67e-40: 129: 100.00		S10A6_HUMAN (2-93): 2.21e-30: 104: 46.74
+	Hs
		1204007 HORN_HUMAN (1-96): 4.87e-33: 122: 25.74		FILA2_HUMAN (4-91): 2.43e-27: 105: 32.96