HitPredict

Interactor 1: MLC1 (P06742)
Myosin light chain alkali
Gene: MLC1

Interactor 2: MYSP2 (P35416)
Paramyosin, short form (Miniparamyosin)
Gene: Prm

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Myosin_tail_1
Common GO terms	GO:0007498 - mesoderm development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 155 Dm			1 640
+	Hs
		472238 MYL3_HUMAN (3-150): 3.04e-64: 196: 36.36		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		472237 MYL3_HUMAN (3-150): 3.04e-64: 196: 36.36		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		437572 MYL1_HUMAN (3-149): 1.75e-63: 194: 39.07		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		472247 MYL3_HUMAN (3-150): 3.04e-64: 196: 36.36		MYH14_HUMAN (293-616): 1.2e-22: 105: 25.62
+	Hs
		773142 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		772704 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Dm
		929121 MLC2_DROME (1-150): 6.95e-52: 163: 37.09		Q59E59_DROME (3-640): 1.32e-26: 118: 13.10
+	Dm
		929129 MLC2_DROME (1-150): 6.95e-52: 163: 37.09		MYSN_DROME (3-640): 1.55e-26: 118: 13.10
+	Dm
		432160 MLC1_DROME (1-155): 2.97e-63: 192: 100.00		MYSA_DROME (3-640): 2.76e-17: 88.5: 10.31
+	Mm
		483499 MYL3_MOUSE (3-150): 9.38e-64: 195: 37.01		MYH6_MOUSE (14-472): 1.27e-15: 83.1: 9.76
+	Hs
		776792 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		MYH11_HUMAN (151-636): 2.1e-24: 111: 10.94
+	Hs
		573929 MYL6B_HUMAN (3-149): 1.9e-45: 149: 35.10		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		573928 MYL6B_HUMAN (3-149): 1.9e-45: 149: 35.10		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		952590 MYL6_HUMAN (1-150): 1.2e-52: 165: 37.66		MYH14_HUMAN (293-616): 1.2e-22: 105: 25.62
+	Hs
		573968 MYL6B_HUMAN (3-149): 1.9e-45: 149: 35.10		MYH14_HUMAN (293-616): 1.2e-22: 105: 25.62
+	Ce
		386947 MLE_CAEEL (12-151): 5.7e-49: 156: 41.26		MYO4_CAEEL (69-638): 6.13e-14: 77.7: 14.01
+	Gg
		387172 MYL6_CHICK (1-150): 4.09e-52: 164: 37.01		MYH11_CHICK (1-364): 5.6e-11: 68.1: 8.24
+	Ce
		386959 MLE_CAEEL (12-151): 5.7e-49: 156: 41.26		MYO1_CAEEL (123-609): 4.47e-13: 74.8: 12.35
+	Ce
		556462 MLE_CAEEL (12-151): 5.7e-49: 156: 41.26		MYO3_CAEEL (56-636): 3.36e-11: 68.8: 10.78
+	Ce
		556469 MLE_CAEEL (12-151): 5.7e-49: 156: 41.26		MYO2_CAEEL (182-607): 3.66e-11: 68.6: 16.45