HitPredict

Interactor 1: H2B1J (P06899)
Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r)
Gene: H2BC11

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~WD40
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 626
+	Hs
		659946 H2B1O_HUMAN (1-126): 2.8e-54: 167: 98.41		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		1163212 H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		256990 H2B1K_HUMAN (1-126): 1.27e-53: 166: 99.21		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		981105 H2B1C_HUMAN (1-126): 1.04e-53: 166: 98.41		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		946885 H2B1D_HUMAN (1-126): 3.08e-53: 164: 97.62		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		1163099 H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21		DDB2_HUMAN (201-625): 2.11e-70: 235: 21.51
+	Hs
		754923 H2B1B_HUMAN (1-126): 1.42e-53: 166: 97.62		DDB2_HUMAN (201-625): 2.11e-70: 235: 21.51
+	Hs
		1163122 H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21		FBXW7_HUMAN (247-571): 4.45e-61: 217: 13.72
+	Sc
		381680 H2B2_YEAST (3-125): 8.57e-37: 123: 70.73		CMR1_YEAST (159-623): 1.95e-74: 249: 23.50
+	Sc
		381328 H2B1_YEAST (3-125): 2.76e-36: 122: 70.73		CMR1_YEAST (159-623): 1.95e-74: 249: 23.50
+	Hs
		449697 H2B1J_HUMAN (1-126): 6.16e-54: 166: 100.00		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		754780 H2B1B_HUMAN (1-126): 1.42e-53: 166: 97.62		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		964984 H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		209241 H2B1C_HUMAN (1-126): 1.04e-53: 166: 98.41		PRP4_HUMAN (401-624): 8.47e-40: 154: 15.09
+	Hs
		261413 H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21		TBL1X_HUMAN (248-479): 5.35e-39: 153: 13.67
+	Hs
		1066326 H2B2E_HUMAN (1-126): 5.71e-54: 166: 99.21		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55
+	Hs
		754817 H2B1B_HUMAN (1-126): 1.42e-53: 166: 97.62		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55
+	Hs
		980722 H2B1C_HUMAN (1-126): 1.04e-53: 166: 98.41		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55