HitPredict

Interactor 1: SSF1 (P38789)
Ribosome biogenesis protein SSF1
Gene: SSF1

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	37968396, 11864607
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Brix~Brix
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 453 Sc			1 291
+	Sc
		994470 SSF2_YEAST (1-453): 0: 538: 94.04		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Sc
		733815 SSF1_YEAST (1-453): 0: 544: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		733976 SSF2_YEAST (1-453): 0: 538: 94.04		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		754857 SSF1_YEAST (1-453): 0: 544: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		755350 SSF2_YEAST (1-453): 0: 538: 94.04		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Hs
		1255217 SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33		BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91
+	Sc
		754856 SSF1_YEAST (1-453): 0: 544: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		754935 SSF1_YEAST (1-453): 0: 544: 100.00		SSF2_YEAST (10-197): 8.32e-33: 127: 15.17
+	Hs
		1343138 SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87