HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: MAST2 (Q6P0Q8)
Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)
Gene: MAST2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007010 - cytoskeleton organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 1798
+	Hs
		418981 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		MAST2_HUMAN (1-1798): 0: 1268: 100.00
+	Hs
		434394 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		MAST2_HUMAN (1-1798): 0: 1268: 100.00
+	Hs
		111618 K7ENT6_HUMAN (72-284): 1.3e-55: 181: 77.00		AKT3_HUMAN (362-857): 1.24e-153: 482: 28.77
+	Hs
		418963 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		KPCD1_HUMAN (68-854): 1.37e-155: 503: 17.68
+	Hs
		451333 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		AKT3_HUMAN (362-857): 1.24e-153: 482: 28.77
+	Hs
		434350 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		AKT2_HUMAN (361-846): 1.68e-153: 481: 28.06
+	Hs
		434349 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		AKT1_HUMAN (361-846): 3.61e-153: 480: 28.60
+	Hs
		932075 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		AKT3_HUMAN (362-857): 1.24e-153: 482: 28.77
+	Hs
		99847 F5H7S3_HUMAN (41-280): 5.4e-33: 123: 73.75		AKT3_HUMAN (362-857): 1.24e-153: 482: 28.77
+	Hs
		681779 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		AKT1_HUMAN (361-846): 3.61e-153: 480: 28.60