Interactor 1: DPOLA (P09884)
DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)
Gene: POLA1

Interactor 2: PRI2 (P49643)
DNA primase large subunit (DNA primase 58 kDa subunit) (p58)
Gene: PRIM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 22593576, 28757209
Identification Methods biochemical, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_B~DNA_primase_lrg, DNA_primase_lrg~zf-DNA_Pol
Common GO terms GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer
GO:0006270 - DNA replication initiation
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1462
Hs

1 509
+ Sp
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024