HitPredict

Interactor 1: SEC4 (P07560)
Ras-related protein SEC4 (Suppressor of RHO3 protein 6)
Gene: SEC4

Interactor 2: SED5 (Q01590)
Integral membrane protein SED5
Gene: SED5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	16107716
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006906 - vesicle fusion
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 215 Sc			1 340
+	Sc
		376333 YPT1_YEAST (13-215): 1.77e-84: 250: 47.09		SED5_YEAST (1-340): 6.97e-64: 207: 100.00
+	Hs
		976240 RB11A_HUMAN (10-215): 1.17e-82: 246: 39.44		STX5_HUMAN (1-324): 1.37e-52: 178: 29.01
+	Hs
		981310 RAB1A_HUMAN (10-215): 7.21e-85: 251: 49.28		STX12_HUMAN (78-328): 2.58e-47: 162: 17.06
+	Sc
		376348 YPT1_YEAST (13-215): 1.77e-84: 250: 47.09		TLG2_YEAST (3-339): 8.24e-45: 159: 13.54
+	Hs
		189497 RAB1A_HUMAN (10-215): 7.21e-85: 251: 49.28		STX7_HUMAN (95-320): 2.59e-45: 157: 18.50
+	Hs
		976388 RB11A_HUMAN (10-215): 1.17e-82: 246: 39.44		STX12_HUMAN (78-328): 2.58e-47: 162: 17.06
+	Sc
		458611 SEC4_YEAST (1-215): 2.16e-82: 245: 100.00		TLG2_YEAST (3-339): 8.24e-45: 159: 13.54
+	Hs
		189495 RB11A_HUMAN (10-215): 1.17e-82: 246: 39.44		STX7_HUMAN (95-320): 2.59e-45: 157: 18.50
+	Mm
		976725 RB11A_MOUSE (10-215): 1.17e-82: 246: 39.44		STX12_MOUSE (78-323): 2.16e-45: 157: 18.22
+	Hs
		1155361 RB11B_HUMAN (10-215): 2.38e-79: 238: 38.14		STX12_HUMAN (78-328): 2.58e-47: 162: 17.06
+	Hs
		976241 RB11A_HUMAN (10-215): 1.17e-82: 246: 39.44		STX3_HUMAN (90-321): 5.47e-44: 154: 12.39
+	Hs
		189585 RB11B_HUMAN (10-215): 2.38e-79: 238: 38.14		STX7_HUMAN (95-320): 2.59e-45: 157: 18.50
+	Hs
		955926 RAB8A_HUMAN (13-211): 2.95e-79: 237: 52.00		STX3_HUMAN (90-321): 5.47e-44: 154: 12.39
+	Sc
		376281 YPT1_YEAST (13-215): 1.77e-84: 250: 47.09		PEP12_YEAST (83-320): 2.31e-15: 77.3: 16.60