Protein: SED5
Integral membrane protein SED5

Gene: SED5
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: Q01590

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005801 - cis-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

646198

SLY1
Protein SLY1

18

20

Small-scale

0.989

High

646262

SEC22
Protein transport protein SEC22

14

20

Small-scale

0.985

High

803093

GOSR1
Golgi SNAP receptor complex member 1

9

20

Small-scale

0.975

High

779506

YKT6
Synaptobrevin homolog YKT6

10

20

Small-scale

0.972

High

1031147

VTI1
t-SNARE VTI1

6

20

Small-scale

0.951

High

743474

SEC17
Alpha-soluble NSF attachment protein

6

20

Small-scale

0.935

High

673645

BOS1
Protein transport protein BOS1

10

0

Small-scale

0.927

High

751600

SNC2
Synaptobrevin homolog 2

3

20

Small-scale

0.845

High

1031153

NYV1
Vacuolar v-SNARE NYV1

2

20

Small-scale

0.778

High

652937

BET1
Protein transport protein BET1

10

20

Small-scale

0.757

High

851253

SFT1
Protein transport protein SFT1

6

1

Small-scale

0.739

High

376333

YPT1
GTP-binding protein YPT1

4

12

Small-scale

0.696

High

825239

SEC24
Protein transport protein SEC24

4

7

Small-scale

0.692

High

582507

SEC23
Protein transport protein SEC23

3

6

Small-scale

0.640

High

919119

COG2
Conserved oligomeric Golgi complex subunit 2

2

0

Small-scale

0.618

High

818574

COG3
Conserved oligomeric Golgi complex subunit 3

2

0

Small-scale

0.616

High

1031152

GET3
ATPase GET3

2

3

Small-scale

0.600

High

1031145

TLG1
t-SNARE affecting a late Golgi compartment protein 1

2

20

Small-scale

0.595

High

922196

PRA1
Prenylated Rab acceptor 1

2

1

Small-scale

0.594

High

633568

SAR1
Small COPII coat GTPase SAR1

2

20

Small-scale

0.571

High

744065

ANP1
Mannan polymerase II complex ANP1 subunit

2

2

Small-scale

0.571

High

745382

EMP24
Endosomal protein P24B

2

2

Small-scale

0.571

High

779663

YPT52
GTP-binding protein YPT52

2

18

Small-scale

0.571

High

932618

TMEDA
Endoplasmic reticulum vesicle protein 25

2

3

Small-scale

0.571

High

1031148

ERV41
ER-derived vesicles protein ERV41

2

6

Small-scale

0.571

High

1031149

ERP1
Protein ERP1

2

3

Small-scale

0.571

High

916968

COG1
Conserved oligomeric Golgi complex subunit 1

2

0

Small-scale

0.569

High

661733

VAN1
Mannan polymerase I complex VAN1 subunit

2

2

Small-scale

0.552

High

698151

KRE2
Glycolipid 2-alpha-mannosyltransferase

2

7

Small-scale

0.552

High

592785

ERD1
Protein ERD1

1

2

High-throughput

0.541

High

673671

USO1
Intracellular protein transport protein USO1

1

3

Small-scale

0.501

High

758134

CASP
Protein CASP

1

5

Small-scale

0.501

High

1031154

ERP3
Protein ERP3

1

5

High-throughput

0.481

High

536157

ARF1
ADP-ribosylation factor 1

1

10

Small-scale

0.479

High

616442

SEC18
Vesicular-fusion protein SEC18

1

20

Small-scale

0.479

High

649846

VPS34
Phosphatidylinositol 3-kinase VPS34

1

2

High-throughput

0.479

High

795495

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

801703

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

3

Small-scale

0.479

High

805168

SFB3
SED5-binding protein 3

1

7

Small-scale

0.479

High

925283

SFB2
SED5-binding protein 2

1

7

Small-scale

0.479

High

925313

COG6
Conserved oligomeric Golgi complex subunit 6

1

1

Small-scale

0.479

High

1031142

BECN1
Vacuolar protein sorting-associated protein 30

1

1

High-throughput

0.479

High

1031150

COG4
Conserved oligomeric Golgi complex subunit 4

1

1

Small-scale

0.479

High

1031151

ATG9
Autophagy-related protein 9

1

5

High-throughput

0.479

High

918758

NNF2
Protein NNF2

1

0

High-throughput

0.460

High

458602

SEC4
Ras-related protein SEC4

1

14

Small-scale

0.445

High

564759

ATC1
Calcium-transporting ATPase 1

1

3

Small-scale

0.445

High

698193

KTR1
Alpha-1,2 mannosyltransferase KTR1

1

7

Small-scale

0.445

High

763697

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

4

Small-scale

0.445

High

792719

MNN2
Alpha-1,2-mannosyltransferase MNN2

1

1

Small-scale

0.445

High

794067

KTR4
Probable mannosyltransferase KTR4

1

7

Small-scale

0.445

High

800392

YPT31
GTP-binding protein YPT31/YPT8

1

18

Small-scale

0.445

High

809125

AKR1
Palmitoyltransferase AKR1

1

6

Small-scale

0.445

High

811574

MNN9
Mannan polymerase complexes subunit MNN9

1

2

Small-scale

0.445

High

813606

ERP2
Protein ERP2

1

4

Small-scale

0.445

High

813920

ERV46
ER-derived vesicles protein ERV46

1

6

Small-scale

0.445

High

825974

GVP36
Protein GVP36

1

1

Small-scale

0.445

High

863615

MNN11
Probable alpha-1,6-mannosyltransferase MNN11

1

1

Small-scale

0.445

High

863822

ATG27
Autophagy-related protein 27

1

2

Small-scale

0.445

High

893402

MNN10
Probable alpha-1,6-mannosyltransferase MNN10

1

1

Small-scale

0.445

High

909759

YPT32
GTP-binding protein YPT32/YPT11

1

18

Small-scale

0.445

High

917971

ERV14
ER-derived vesicles protein ERV14

1

2

Small-scale

0.445

High

600707

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.439

High

672445

STE50
Protein STE50

1

1

High-throughput

0.439

High

735657

SMY1
Kinesin-related protein SMY1

1

2

High-throughput

0.439

High

777098

BDF1
Bromodomain-containing factor 1

1

1

High-throughput

0.439

High

815047

SNF7
Vacuolar-sorting protein SNF7

1

2

High-throughput

0.439

High

866278

HMS2
Probable transcription factor HMS2

1

1

High-throughput

0.439

High

1031143

RT17
Small ribosomal subunit protein uS17m

1

2

High-throughput

0.439

High

481729

HSP73
Heat shock protein SSA3

1

8

Small-scale

0.437

High

707930

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

1031144

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

560286

KEX2
Kexin

1

0

Small-scale

0.426

High

676867

RER1
Protein RER1

1

0

Small-scale

0.426

High

754412

SEC66
Translocation protein SEC66

1

0

Small-scale

0.426

High

806240

SVP26
Protein SVP26

1

0

Small-scale

0.426

High

849655

EMP47
Protein EMP47

1

0

Small-scale

0.426

High

923818

YIF1
Protein transport protein YIF1

1

0

Small-scale

0.426

High

524875

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.407

High

527453

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.407

High

545937

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.407

High

742199

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.407

High

794054

KTR3
Probable mannosyltransferase KTR3

1

7

Small-scale

0.407

High

797559

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

1

Small-scale

0.407

High

819537

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.407

High

865825

HOC1
Putative glycosyltransferase HOC1

1

0

High-throughput

0.282

High

677768

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

873831

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.251

Low

1031146

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.251

Low

815101

SS120
Protein SSP120

1

0

Small-scale

0.232

Low

924480

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025