HitPredict

Interactor 1: SYEP (P07814)
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]
Gene: EPRS1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25796446, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1512 Hs			1 504
+	Hs
		131673 SYEP_HUMAN (1-1512): 0: 1815: 100.00		WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54
+	Hs
		460460 SYEP_HUMAN (1-1512): 0: 1815: 100.00		NEDD4_HUMAN (40-504): 3.86e-95: 315: 19.26
+	Hs
		460581 SYEP_HUMAN (1-1512): 0: 1815: 100.00		HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09
+	Sc
		815484 SYEC_YEAST (5-707): 0: 725: 42.04		RSP5_YEAST (3-504): 1.28e-97: 314: 15.25
+	Hs
		131816 SYQ_HUMAN (159-704): 0: 634: 31.19		WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54
+	Hs
		687710 SYTC_HUMAN (703-1410): 0: 582: 15.62		ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47
+	Hs
		687647 SYTC_HUMAN (703-1410): 0: 582: 15.62		YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00
+	Sc
		750268 SYEC_YEAST (5-707): 0: 725: 42.04		PRP40_YEAST (177-503): 2.01e-52: 188: 12.87
+	Sc
		858122 SYEC_YEAST (5-707): 0: 725: 42.04		TOM1_YEAST (260-504): 8.95e-40: 156: 12.10
+	Hs
		868199 SYQ_HUMAN (159-704): 0: 634: 31.19		HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09
+	Hs
		687690 SYTC_HUMAN (703-1410): 0: 582: 15.62		HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09
+	Hs
		861756 SYTM_HUMAN (774-1411): 1.52e-151: 480: 14.87		NEDD4_HUMAN (40-504): 3.86e-95: 315: 19.26
+	Sc
		416100 SYTC_YEAST (704-1407): 2.35e-167: 523: 14.95		PRP40_YEAST (177-503): 2.01e-52: 188: 12.87
+	Hs
		687734 SYTC_HUMAN (703-1410): 0: 582: 15.62		WWOX_HUMAN (166-263): 7.43e-29: 120: 30.61
+	Sc
		416151 SYTC_YEAST (704-1407): 2.35e-167: 523: 14.95		TOM1_YEAST (260-504): 8.95e-40: 156: 12.10
+	Sc
		815496 SYEM_YEAST (197-509): 8.13e-102: 338: 22.25		RSP5_YEAST (3-504): 1.28e-97: 314: 15.25