Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: S12A3 (P55017)
Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter)
Gene: SLC12A3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 23482560, unassigned3795
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0016324 - apical plasma membrane
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 732
Hs

1 1021
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025