HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: S12A5 (Q9H2X9)
Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter)
Gene: SLC12A5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0019901 - protein kinase binding GO:0043025 - neuronal cell body
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 1139
+	Hs
		461926 HS90A_HUMAN (1-724): 0: 1069: 85.25		S12A5_HUMAN (1-1139): 0: 1205: 100.00
+	Hs
		468886 HS90B_HUMAN (1-724): 0: 1083: 100.00		S12A6_HUMAN (2-1139): 0: 1057: 68.33
+	Hs
		468963 HS90B_HUMAN (1-724): 0: 1083: 100.00		S12A7_HUMAN (1-1139): 0: 1054: 69.83
+	Hs
		468920 HS90B_HUMAN (1-724): 0: 1083: 100.00		S12A4_HUMAN (4-1139): 0: 1045: 66.93
+	Hs
		462015 HS90A_HUMAN (1-724): 0: 1069: 85.25		S12A6_HUMAN (2-1139): 0: 1057: 68.33
+	Hs
		462089 HS90A_HUMAN (1-724): 0: 1069: 85.25		S12A7_HUMAN (1-1139): 0: 1054: 69.83
+	Hs
		462049 HS90A_HUMAN (1-724): 0: 1069: 85.25		S12A4_HUMAN (4-1139): 0: 1045: 66.93
+	Hs
		468219 HS90B_HUMAN (1-724): 0: 1083: 100.00		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Hs
		461312 HS90A_HUMAN (1-724): 0: 1069: 85.25		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Sc
		578918 HSC82_YEAST (13-724): 0: 920: 60.22		AGP1_YEAST (189-694): 4.97e-74: 260: 13.73