HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1150
+	Hs
		468886 HS90B_HUMAN (19-732): 0: 1057: 86.13		S12A6_HUMAN (1-1150): 0: 1255: 100.00
+	Hs
		461926 HS90A_HUMAN (1-732): 0: 1085: 100.00		S12A5_HUMAN (44-1150): 0: 1094: 66.78
+	Hs
		462049 HS90A_HUMAN (1-732): 0: 1085: 100.00		S12A4_HUMAN (100-1150): 0: 1091: 77.68
+	Hs
		468795 HS90B_HUMAN (19-732): 0: 1057: 86.13		S12A5_HUMAN (44-1150): 0: 1094: 66.78
+	Hs
		468920 HS90B_HUMAN (19-732): 0: 1057: 86.13		S12A4_HUMAN (100-1150): 0: 1091: 77.68
+	Hs
		462089 HS90A_HUMAN (1-732): 0: 1085: 100.00		S12A7_HUMAN (71-1150): 0: 1058: 69.37
+	Hs
		468963 HS90B_HUMAN (19-732): 0: 1057: 86.13		S12A7_HUMAN (71-1150): 0: 1058: 69.37
+	Hs
		461312 HS90A_HUMAN (1-732): 0: 1085: 100.00		S12A3_HUMAN (60-1149): 0: 726: 21.22
+	Hs
		468219 HS90B_HUMAN (19-732): 0: 1057: 86.13		S12A3_HUMAN (60-1149): 0: 726: 21.22