HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: TB182 (Q9C0C2)
182 kDa tankyrase-1-binding protein
Gene: TNKS1BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005912 - adherens junction GO:0019899 - enzyme binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1729
+	Hs
		440198 LCK_HUMAN (1-512): 0: 585: 63.62		TB182_HUMAN (1-1721): 0: 1216: 100.00
+	Hs
		463316 LYN_HUMAN (1-512): 0: 621: 100.00		MUC1_HUMAN (3-671): 1.52e-31: 137: 10.86
+	Hs
		319045 LYN_HUMAN (1-512): 0: 621: 100.00		K0754_HUMAN (407-866): 1.9e-23: 111: 12.11
+	Hs
		440195 LCK_HUMAN (1-512): 0: 585: 63.62		K1671_HUMAN (1548-1728): 3.58e-33: 143: 32.29
+	Hs
		557066 SRC_HUMAN (1-510): 0: 591: 51.97		MUC1_HUMAN (3-671): 1.52e-31: 137: 10.86
+	Hs
		439935 LCK_HUMAN (1-512): 0: 585: 63.62		MUC1_HUMAN (3-671): 1.52e-31: 137: 10.86
+	Hs
		463610 LYN_HUMAN (1-512): 0: 621: 100.00		MICA3_HUMAN (1-579): 1.99e-11: 71.6: 10.53
+	Hs
		463690 LYN_HUMAN (1-512): 0: 621: 100.00		CBP_HUMAN (268-866): 1.95e-09: 65: 10.05
+	Mm
		107051 LYN_MOUSE (1-512): 0: 621: 96.09		F8VPR5_MOUSE (195-841): 2.82e-09: 64.7: 9.96
+	Hs
		66953 SRC_HUMAN (1-510): 0: 591: 51.97		L37A2_HUMAN (1-489): 6.84e-16: 86.2: 10.89
+	Hs
		440773 FYN_HUMAN (1-510): 0: 583: 54.31		MAGL2_HUMAN (285-834): 2.66e-16: 87.4: 9.42
+	Hs
		473455 HCK_HUMAN (1-512): 0: 601: 70.70		CBP_HUMAN (268-866): 1.95e-09: 65: 10.05
+	Hs
		362149 ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88		MUC1_HUMAN (3-671): 1.52e-31: 137: 10.86
+	Hs
		557412 SRC_HUMAN (1-510): 0: 591: 51.97		CBP_HUMAN (268-866): 1.95e-09: 65: 10.05
+	Hs
		440738 FYN_HUMAN (1-510): 0: 583: 54.31		MAGE1_HUMAN (26-344): 2.45e-09: 64.5: 18.41
+	Hs
		362312 ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88		HUWE1_HUMAN (235-607): 2.46e-15: 84.5: 16.79
+	Mm
		107057 CSK_MOUSE (64-503): 1.53e-171: 493: 38.63		F8VPR5_MOUSE (195-841): 2.82e-09: 64.7: 9.96