Protein: TB182
182 kDa tankyrase-1-binding protein

Gene: TB182, TNKS1BP1
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q9C0C2

Gene Ontology (top 5):
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000792 - heterochromatin
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1420828

CNOT7
CCR4-NOT transcription complex subunit 7

6

2

Small-scale

0.729

High

866813

CAZA2
F-actin-capping protein subunit alpha-2

5

6

Small-scale

0.709

High

1420830

CNO11
CCR4-NOT transcription complex subunit 11

5

1

Small-scale

0.709

High

170339

AURKA
Aurora kinase A

4

8

High-throughput

0.694

High

1397035

CNO6L
CCR4-NOT transcription complex subunit 6-like

4

4

Small-scale

0.691

High

867402

CAPZB
F-actin-capping protein subunit beta

4

5

Small-scale

0.687

High

1420822

CNOT2
CCR4-NOT transcription complex subunit 2

4

8

Small-scale

0.683

High

1420824

WRP73
WD repeat-containing protein WRAP73

3

6

High-throughput

0.667

High

64111

CNOT1
CCR4-NOT transcription complex subunit 1

3

1

Small-scale

0.650

High

1420813

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

3

19

Small-scale

0.647

High

332443

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

2

19

Small-scale

0.643

High

897471

TOB1
Protein Tob1

3

0

Small-scale

0.634

High

949502

NANO2
Nanos homolog 2

2

1

High-throughput

0.628

High

1326435

MINK1
Misshapen-like kinase 1

2

5

High-throughput

0.628

High

1420835

FBW1A
F-box/WD repeat-containing protein 1A

2

10

High-throughput

0.628

High

1123102

FHL2
Four and a half LIM domains protein 2

2

14

Small-scale

0.618

High

480387

MMP7
Matrilysin

3

1

High-throughput

0.609

High

275462

GA45B
Growth arrest and DNA damage-inducible protein GADD45 beta

2

0

High-throughput

0.602

High

273926

CNOT3
CCR4-NOT transcription complex subunit 3

2

13

Small-scale

0.601

High

915178

CAZA1
F-actin-capping protein subunit alpha-1

2

6

Small-scale

0.601

High

1420815

CNO10
CCR4-NOT transcription complex subunit 10

2

1

Small-scale

0.601

High

1420832

CNOT6
CCR4-NOT transcription complex subunit 6

2

3

Small-scale

0.601

High

1215816

RC3H1
Roquin-1

3

3

Small-scale

0.585

High

582947

EZRI
Ezrin

2

11

High-throughput

0.584

High

1115992

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

13

High-throughput

0.584

High

1336835

TNR6A
Trinucleotide repeat-containing gene 6A protein

2

20

Small-scale

0.584

High

1420826

ZRAN1
Ubiquitin thioesterase ZRANB1

2

9

High-throughput

0.584

High

1365353

CNOT9
CCR4-NOT transcription complex subunit 9

2

2

Small-scale

0.571

High

998002

CSK21
Casein kinase II subunit alpha

1

17

High-throughput

0.550

High

64809

EPAB2
Embryonic polyadenylate-binding protein 2

1

1

High-throughput

0.536

High

220013

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.536

High

302084

SEGN
Secretagogin

1

9

High-throughput

0.536

High

407707

S100B
Protein S100-B

1

3

High-throughput

0.536

High

564342

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

848715

MAGA9
Melanoma-associated antigen 9

1

10

High-throughput

0.536

High

976544

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.536

High

1310384

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1347596

UHMK1
Serine/threonine-protein kinase Kist

1

6

High-throughput

0.536

High

1361405

NANO1
Nanos homolog 1

1

1

High-throughput

0.536

High

1404373

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.536

High

1420817

GPBL1
Vasculin-like protein 1

1

1

High-throughput

0.536

High

1420825

NLK
Serine/threonine-protein kinase NLK

1

8

High-throughput

0.536

High

1219887

OBI1
ORC ubiquitin ligase 1

2

1

High-throughput

0.533

High

638516

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.513

High

1179030

S35G1
Solute carrier family 35 member G1

1

1

High-throughput

0.489

High

129402

MEN1
Menin

1

4

High-throughput

0.479

High

157824

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.479

High

173325

XPO1
Exportin-1

1

11

High-throughput

0.479

High

176542

GRRE1
Granule associated Rac and RHOG effector protein 1

1

2

High-throughput

0.479

High

180919

TIF1A
Transcription intermediary factor 1-alpha

1

20

Small-scale

0.479

High

242848

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

246926

KDM1A
Lysine-specific histone demethylase 1A

1

8

High-throughput

0.479

High

247422

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

7

High-throughput

0.479

High

248081

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

274234

ANR17
Ankyrin repeat domain-containing protein 17

1

18

High-throughput

0.479

High

299362

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

375920

RASK
GTPase KRas

1

11

High-throughput

0.479

High

396895

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

440198

LCK
Tyrosine-protein kinase Lck

1

16

High-throughput

0.479

High

459744

PROF1
Profilin-1

1

5

High-throughput

0.479

High

463749

LYN
Tyrosine-protein kinase Lyn

1

17

High-throughput

0.479

High

540663

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

556328

CADH1
Cadherin-1

1

5

High-throughput

0.479

High

589622

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

613454

VINC
Vinculin

1

4

High-throughput

0.479

High

626356

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

High-throughput

0.479

High

688310

TTP
mRNA decay activator protein ZFP36

1

5

High-throughput

0.479

High

696436

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

714405

PML
Protein PML

1

20

High-throughput

0.479

High

714959

EF1D
Elongation factor 1-delta

1

3

Small-scale

0.479

High

715760

MARCS
Myristoylated alanine-rich C-kinase substrate

1

7

High-throughput

0.479

High

767495

RADI
Radixin

1

10

High-throughput

0.479

High

791695

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

831387

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

862428

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

888317

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

891305

GSK3A
Glycogen synthase kinase-3 alpha

1

11

High-throughput

0.479

High

891774

GSK3B
Glycogen synthase kinase-3 beta

1

13

High-throughput

0.479

High

896633

VASP
Vasodilator-stimulated phosphoprotein

1

5

High-throughput

0.479

High

905115

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

930047

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

7

High-throughput

0.479

High

935103

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

953085

ACTB
Actin, cytoplasmic 1

1

12

High-throughput

0.479

High

956477

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

975226

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

1041264

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

1045742

TF65
Transcription factor p65

1

13

High-throughput

0.479

High

1049753

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1051852

EF1A2
Elongation factor 1-alpha 2

1

4

High-throughput

0.479

High

1101017

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

1108124

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

1110054

HDAC1
Histone deacetylase 1

1

13

High-throughput

0.479

High

1115043

CUL4A
Cullin-4A

1

10

High-throughput

0.479

High

1121331

TRI14
Tripartite motif-containing protein 14

1

7

High-throughput

0.479

High

1137511

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1138613

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1140813

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

1145099

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

1155737

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.479

High

1156203

ZYX
Zyxin

1

12

High-throughput

0.479

High

1156592

CCDC6
Coiled-coil domain-containing protein 6

1

12

High-throughput

0.479

High

1161655

IF16
Gamma-interferon-inducible protein 16

1

7

High-throughput

0.479

High

1241581

CEP85
Centrosomal protein of 85 kDa

1

16

High-throughput

0.479

High

1246975

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1252381

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1255433

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

1258383

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.479

High

1276754

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

13

High-throughput

0.479

High

1289605

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1324362

STK40
Serine/threonine-protein kinase 40

1

4

Small-scale

0.479

High

1368103

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.479

High

1368949

GOGA1
Golgin subfamily A member 1

1

8

High-throughput

0.479

High

1380147

FBXW7
F-box/WD repeat-containing protein 7

1

10

High-throughput

0.479

High

1420660

UNK
RING finger protein unkempt homolog

1

8

High-throughput

0.479

High

1420811

WWTR1
WW domain-containing transcription regulator protein 1

1

14

High-throughput

0.479

High

1420814

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1420818

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

1420819

ANLN
Anillin

1

8

High-throughput

0.479

High

1420820

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1420823

ANFY1
Rabankyrin-5

1

19

High-throughput

0.479

High

1420827

TES
Testin

1

14

High-throughput

0.479

High

1420829

RCOR1
REST corepressor 1

1

11

High-throughput

0.479

High

1420831

BAG5
BAG family molecular chaperone regulator 5

1

2

High-throughput

0.479

High

1420834

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

8

High-throughput

0.479

High

1420836

YTHD2
YTH domain-containing family protein 2

1

8

High-throughput

0.479

High

1420837

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

4

Small-scale

0.479

High

327437

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

630033

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

1181252

ZN750
Zinc finger protein 750

1

0

Small-scale

0.458

High

1356827

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.458

High

1407457

TS101
Tumor susceptibility gene 101 protein

1

0

Small-scale

0.458

High

1420812

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

344312

PTBP3
Polypyrimidine tract-binding protein 3

1

2

High-throughput

0.445

High

1234946

PKHA7
Pleckstrin homology domain-containing family A member 7

1

11

High-throughput

0.445

High

1405523

ZBT18
Zinc finger and BTB domain-containing protein 18

1

7

High-throughput

0.445

High

218741

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.437

High

412574

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

643057

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.437

High

769108

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

1159828

OCLN
Occludin

1

5

High-throughput

0.437

High

1241949

FBX42
F-box only protein 42

1

7

High-throughput

0.437

High

1384431

PF21A
PHD finger protein 21A

1

16

High-throughput

0.437

High

1420816

RC3H2
Roquin-2

1

18

Small-scale

0.437

High

1420821

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

3

High-throughput

0.437

High

1420833

ALK
ALK tyrosine kinase receptor

1

11

High-throughput

0.437

High

1401866

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1420838

CCD61
Centrosomal protein CCDC61

1

0

Small-scale

0.426

High

1420709

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.407

High

1325722

RIBC1
RIB43A-like with coiled-coils protein 1

3

0

High-throughput

0.345

High

1399939

FACOS
FANCD2 opposite strand protein

2

0

High-throughput

0.313

High

1192025

AX2R
Annexin-2 receptor

1

0

High-throughput

0.279

Low

1356189

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.249

Low

62593

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025