HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 525
+	Hs
		962122 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		988416 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		1015491 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		955247 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		961998 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		988324 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		1015396 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		988289 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		ANK2_HUMAN (261-522): 9.95e-39: 153: 14.82
+	Hs
		955105 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		295481 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PSD10_HUMAN (275-408): 8.83e-40: 145: 26.12
+	Hs
		962216 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ANS1B_HUMAN (266-509): 9.57e-34: 138: 14.54
+	Hs
		962478 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		Q9H4D1_HUMAN (39-330): 1.3e-30: 128: 11.48
+	Hs
		943894 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		RIPK4_HUMAN (5-271): 3.17e-20: 96.5: 11.07
+	Hs
		962626 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		988816 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		466521 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		1015901 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		962014 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		988335 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		955127 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29