HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 525
+	Hs
		988416 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		1015491 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		962122 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		988324 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		1015396 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		955105 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		988289 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		ANK2_HUMAN (261-522): 9.95e-39: 153: 14.82
+	Hs
		961998 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		295481 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		PSD10_HUMAN (275-408): 8.83e-40: 145: 26.12
+	Hs
		601494 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		1433575 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		601270 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		988816 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		1104487 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		1015901 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		955746 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		943894 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		RIPK4_HUMAN (5-271): 3.17e-20: 96.5: 11.07
+	Hs
		988335 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		955127 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		962014 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29