Interactor 1: 4F2 (P08195)
Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
Gene: SLC3A2
Interactor 2: LAT2 (Q9UHI5)
Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8)
Gene: SLC7A8
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 1.00 | 0.890 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 33961781, unassigned1304, unassigned3795 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AA_permease_2~Alpha-amylase, AA_permease_2~SLC3A2_N |
| Common GO terms | GO:0005886 - plasma membrane GO:0006865 - amino acid transport GO:0009925 - basal plasma membrane GO:0015175 - neutral L-amino acid transmembrane transporter activity GO:0015180 - L-alanine transmembrane transporter activity and 10 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
