HitPredict

Interactor 1: SRPRA (P08240)
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRPRA

Interactor 2: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 1297
+	Hs
		465367 SRPRA_HUMAN (1-638): 0: 783: 100.00		IGF1R_HUMAN (9-1265): 0: 1177: 55.66
+	Hs
		469007 SRPRA_HUMAN (1-638): 0: 783: 100.00		EPHA8_HUMAN (649-1268): 5.38e-173: 541: 24.11
+	Hs
		469233 SRPRA_HUMAN (1-638): 0: 783: 100.00		ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46
+	Hs
		179594 SRPRA_HUMAN (1-638): 0: 783: 100.00		MUSK_HUMAN (973-1242): 8.34e-67: 245: 42.61
+	Hs
		411213 SRPRA_HUMAN (1-638): 0: 783: 100.00		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91
+	Hs
		469087 SRPRA_HUMAN (1-638): 0: 783: 100.00		NTRK3_HUMAN (957-1242): 2.06e-62: 231: 40.84
+	Hs
		468976 SRPRA_HUMAN (1-638): 0: 783: 100.00		FGFR1_HUMAN (948-1294): 6.84e-59: 221: 35.90
+	Hs
		468998 SRPRA_HUMAN (1-638): 0: 783: 100.00		ERBB3_HUMAN (2-296): 6.35e-34: 144: 18.24
+	Hs
		439621 SRPRA_HUMAN (1-638): 0: 783: 100.00		INSR_HUMAN (5-179): 6.45e-12: 72.8: 20.67
+	Hs
		468972 SRPRA_HUMAN (1-638): 0: 783: 100.00		ROS1_HUMAN (764-900): 1.06e-10: 68.9: 22.63
+	Hs
		956203 SRP54_HUMAN (320-636): 8.86e-111: 344: 21.45		ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46
+	Hs
		411676 SRP54_HUMAN (320-636): 8.86e-111: 344: 21.45		NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91