HitPredict

Interactor 1: SRPRA (P08240)
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRPRA

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 1620
+	Hs
		956203 SRP54_HUMAN (320-636): 8.86e-111: 344: 21.45		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		463882 SRPRA_HUMAN (1-638): 0: 783: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		179594 SRPRA_HUMAN (1-638): 0: 783: 100.00		MUSK_HUMAN (983-1391): 1.78e-119: 399: 29.98
+	Hs
		468972 SRPRA_HUMAN (1-638): 0: 783: 100.00		ROS1_HUMAN (1039-1461): 3.97e-112: 397: 37.75
+	Hs
		469000 SRPRA_HUMAN (1-638): 0: 783: 100.00		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		439621 SRPRA_HUMAN (1-638): 0: 783: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465367 SRPRA_HUMAN (1-638): 0: 783: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		468981 SRPRA_HUMAN (1-638): 0: 783: 100.00		INSRR_HUMAN (1082-1384): 2.39e-70: 262: 43.46
+	Hs
		411213 SRPRA_HUMAN (1-638): 0: 783: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		469087 SRPRA_HUMAN (1-638): 0: 783: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		468976 SRPRA_HUMAN (1-638): 0: 783: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		411676 SRP54_HUMAN (320-636): 8.86e-111: 344: 21.45		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07