HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 344
+	Hs
		470360 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		992835 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		470361 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		1216259 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Hs
		470370 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		993761 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		1028721 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		1216253 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		1087093 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23
+	Hs
		555446 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		474005 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		PAB4L_HUMAN (1-196): 1.97e-35: 134: 15.94
+	Hs
		470580 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		391681 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		470244 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		1087117 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		RBM28_HUMAN (4-248): 1.53e-12: 70.6: 14.61
+	Hs
		516349 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Sc
		376566 H2A2_YEAST (16-128): 2.5e-59: 180: 80.53		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80