HitPredict

Interactor 1: A0A583ZBW8 (A0A583ZBW8)
HLA-C protein
Gene: HLA-C

Interactor 2: KI2S5 (Q14953)
Killer cell immunoglobulin-like receptor 2DS5 (CD158 antigen-like family member G) (Natural killer-associated transcript 9) (NKAT-9) (CD antigen CD158g)
Gene: KIR2DS5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28685972
Identification Methods	affinity technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	GO:0006955 - immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Hs			1 304
+	Hs
		850913 Q5S3G3_HUMAN (1-365): 2.01e-179: 503: 82.19		KI2S4_HUMAN (1-304): 6.09e-118: 342: 87.83
+	Hs
		850828 Q5S3G3_HUMAN (1-365): 2.01e-179: 503: 82.19		KI2L3_HUMAN (1-304): 4.24e-110: 324: 89.80
+	Hs
		850827 Q5RIP0_HUMAN (1-366): 1.07e-172: 486: 94.81		KI2L3_HUMAN (1-304): 4.24e-110: 324: 89.80
+	Hs
		850806 Q5RIP0_HUMAN (1-366): 1.07e-172: 486: 94.81		KI2L2_HUMAN (1-303): 3.47e-108: 319: 87.79
+	Hs
		850781 Q5RIP0_HUMAN (1-366): 1.07e-172: 486: 94.81		KI2L1_HUMAN (1-303): 1.28e-107: 318: 88.78
+	Hs
		850779 Q5D1W8_HUMAN (1-366): 3.91e-171: 483: 93.44		KI2L1_HUMAN (1-303): 1.28e-107: 318: 88.78
+	Hs
		409455 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		LIRB4_HUMAN (1-241): 2.28e-72: 231: 37.86
+	Hs
		1133831 Q95J06_HUMAN (1-365): 0: 516: 80.55		KI3S1_HUMAN (1-246): 1.07e-59: 196: 36.55
+	Hs
		47606 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		A0A8I5QEB2_HUMAN (1-246): 2.28e-62: 204: 40.96
+	Hs
		409302 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		KI3L2_HUMAN (1-246): 3.36e-59: 197: 39.36
+	Hs
		409383 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		KI3S1_HUMAN (1-246): 1.07e-59: 196: 36.55
+	Hs
		850877 Q5S3G3_HUMAN (1-365): 2.01e-179: 503: 82.19		KI3L2_HUMAN (1-246): 3.36e-59: 197: 39.36
+	Hs
		1133828 Q5SUL5_HUMAN (1-365): 2.51e-177: 498: 80.27		KI3S1_HUMAN (1-246): 1.07e-59: 196: 36.55
+	Hs
		1340138 Q95J06_HUMAN (1-365): 0: 516: 80.55		LIRB1_HUMAN (21-258): 4.24e-40: 149: 34.98
+	Hs
		409456 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		LIRB1_HUMAN (21-258): 4.24e-40: 149: 34.98
+	Hs
		1209906 Q5S3G3_HUMAN (1-365): 2.01e-179: 503: 82.19		LIRB1_HUMAN (21-258): 4.24e-40: 149: 34.98
+	Hs
		409294 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		CEAM6_HUMAN (27-248): 9.1e-23: 98.3: 14.77
+	Hs
		1325618 Q95J06_HUMAN (1-365): 0: 516: 80.55		LIRB2_HUMAN (10-138): 4.92e-16: 80.2: 37.98
+	Hs
		409446 HLAA_HUMAN (1-365): 6.81e-180: 504: 81.92		LIRB2_HUMAN (10-138): 4.92e-16: 80.2: 37.98
+	Hs
		1209905 Q5S3G3_HUMAN (1-365): 2.01e-179: 503: 82.19		LIRB2_HUMAN (10-138): 4.92e-16: 80.2: 37.98