HitPredict

Interactor 1: H2AB1 (P0C5Y9)
Histone H2A-Bbd type 1 (H2A Barr body-deficient) (H2A.B) (H2A.Bbd)
Gene: H2AB1

Interactor 2: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21888893
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 115 Hs			1 185
+	Hs
		472801 H2AB1_HUMAN (1-115): 3e-66: 197: 100.00		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		555444 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		594841 H2A1D_HUMAN (7-109): 4.88e-50: 156: 44.66		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		470349 H2A1_HUMAN (7-109): 4.1e-50: 156: 45.63		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		594840 H2A1D_HUMAN (7-109): 4.88e-50: 156: 44.66		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		391654 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		555335 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		800438 H2A3_HUMAN (7-109): 4.1e-50: 156: 45.63		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		203730 H2A2B_HUMAN (7-109): 2.22e-51: 160: 47.57		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		203696 H2A2C_HUMAN (7-109): 3.16e-50: 157: 45.63		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		316082 H2A2B_HUMAN (7-109): 2.22e-51: 160: 47.57		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		555696 H2AX_HUMAN (7-109): 6.03e-51: 159: 47.57		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		1087137 H2A2C_HUMAN (7-109): 3.16e-50: 157: 45.63		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		470614 H2A1_HUMAN (7-109): 4.1e-50: 156: 45.63		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		315950 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		391702 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		391975 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		1312232 H2AJ_HUMAN (7-109): 1.95e-50: 157: 46.60		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		123160 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		391912 H2A1B_HUMAN (7-109): 7.99e-50: 155: 44.66		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07