Interactor 1: R1A (P0C6U8)
Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Host translation inhibitor nsp1 (Leader protein) (Non-structural protein 1) (nsp1); Non-structural protein 2 (nsp2) (p65 homolog); Papain-like protease nsp3 (PL-PRO) (EC 3.4.19.12) (EC 3.4.22.-) (Non-structural protein 3) (nsp3) (PL2-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase nsp5 (3CL-PRO) (3CLp) (EC 3.4.22.69) (Main protease) (Mpro) (Non-structural protein 5) (nsp5) (SARS coronavirus main proteinase); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); RNA-capping enzyme subunit nsp9 (Non-structural protein 9) (nsp9) (EC 2.7.7.50); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]
Gene: 1a

Interactor 2: VEMP (P59637)
Envelope small membrane protein (E protein) (sM protein)
Gene: E

Species: Severe acute respiratory syndrome-related coronavirus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.43 0.60 0.508

The method score is based on:

Property Details
Experiments 17520018
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016020 - membrane
GO:0044177 - host cell Golgi apparatus
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 4382
Sa

1 76
+ Sa
+ Sa

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Last updated: 15 Jul 2024