HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	25416956, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 446
+	Hs
		1025420 Q5U5U6_HUMAN (1-229): 4.07e-98: 286: 100.00		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		475085 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		475695 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		1025496 Q96C32_HUMAN (1-153): 2.55e-56: 182: 99.35		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		923972 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Mm
		476794 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		TAXB1_MOUSE (13-439): 3.84e-36: 143: 21.23
+	Hs
		476001 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Mm
		476822 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		EP15R_MOUSE (102-435): 2.36e-31: 129: 13.55
+	Rn
		88639 UBC_RAT (1-181): 2.6e-61: 206: 96.13		D3ZJR1_RAT (102-435): 5.71e-30: 125: 13.18
+	Hs
		924056 RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		476091 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		DLG5_HUMAN (77-439): 7.24e-18: 88.6: 10.03
+	Mm
		476700 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		EPS15_MOUSE (75-249): 5.43e-10: 63.6: 11.11
+	Mm
		476930 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		MYH9_MOUSE (144-345): 5.01e-09: 61: 15.05
+	Mm
		476828 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		MYH10_MOUSE (60-417): 4.81e-09: 60.9: 12.06
+	Rn
		1126748 UBC_RAT (1-181): 2.6e-61: 206: 96.13		Q5JC29_RAT (77-225): 3.69e-09: 60.9: 9.93
+	Hs
		476502 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		EP15R_HUMAN (76-252): 1.67e-15: 80.9: 15.25
+	Hs
		475882 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		FKB15_HUMAN (128-441): 4.96e-13: 73.6: 9.49
+	Hs
		475644 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		CENPE_HUMAN (124-345): 3.98e-10: 64.4: 21.34
+	Hs
		475452 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		EPS15_HUMAN (77-234): 4.48e-10: 64: 11.88
+	Hs
		475417 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05