HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1488
+	Hs
		475943 UBC_HUMAN (1-685): 0: 846: 100.00		OTOG_HUMAN (414-1002): 6.41e-30: 132: 12.16
+	Hs
		152577 UBC_HUMAN (1-685): 0: 846: 100.00		KMT2D_HUMAN (751-1487): 2.54e-13: 77.6: 8.66
+	Hs
		475764 UBC_HUMAN (1-685): 0: 846: 100.00		NCOA6_HUMAN (59-1090): 2.41e-13: 77.6: 8.41
+	Hs
		476650 UBC_HUMAN (1-685): 0: 846: 100.00		NCOR2_HUMAN (337-1488): 2.04e-09: 65: 8.15
+	At
		1092118 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q9LIE8_ARATH (931-1488): 2.68e-19: 97: 9.68
+	Mm
		139850 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TCOF_MOUSE (1-1260): 6.98e-49: 193: 30.41
+	Rn
		546259 UBC_RAT (1-108): 1.27e-29: 127: 90.74		MAP1B_RAT (56-1111): 1.17e-45: 183: 10.22
+	Hs
		398152 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PRC2C_HUMAN (35-1393): 5.37e-41: 168: 9.91
+	Hs
		92115 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		NACAM_HUMAN (203-1485): 5.74e-32: 138: 9.82
+	Hs
		924061 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		MILK2_HUMAN (420-909): 2.21e-09: 64.4: 19.48
+	Hs
		924095 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TITIN_HUMAN (91-778): 3.15e-09: 64.2: 9.45
+	Rn
		1144063 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SYNJ1_RAT (321-797): 1.86e-12: 74.6: 12.88