HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: U17L2 (Q6R6M4)
Ubiquitin carboxyl-terminal hydrolase 17 (USP17) (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 2) (Deubiquitinating protein 3) (DUB-3) (Ubiquitin carboxyl-terminal hydrolase 17-like protein 2) (Ubiquitin thioesterase 17-like protein 2) (Ubiquitin-specific-processing protease 17-like protein 2)
Gene: USP17L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	34129829
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 530
+	Hs
		476400 UBC_HUMAN (1-685): 0: 846: 100.00		UBP42_HUMAN (1-505): 1.28e-143: 448: 44.49
+	Hs
		476493 UBC_HUMAN (1-685): 0: 846: 100.00		UBP36_HUMAN (7-516): 6.17e-126: 396: 35.31
+	Hs
		476147 UBC_HUMAN (1-685): 0: 846: 100.00		UBP7_HUMAN (6-500): 1.61e-101: 331: 19.16
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (46-380): 8.02e-107: 330: 27.06
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (29-389): 7.53e-107: 328: 25.85
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (7-380): 5.03e-102: 320: 25.12
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (64-374): 1.29e-100: 314: 25.75
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (79-376): 6.54e-100: 307: 25.75
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (79-376): 2.79e-98: 303: 25.15
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (69-380): 4.68e-97: 304: 27.07
+	At
		1210479 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP15_ARATH (10-445): 7.21e-112: 355: 30.28
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (10-373): 3.25e-99: 309: 26.49
+	At
		1092066 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP12_ARATH (12-512): 5.2e-113: 362: 20.61
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (13-513): 4.98e-112: 359: 19.75
+	At
		1092065 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP15_ARATH (10-445): 7.21e-112: 355: 30.28
+	Hs
		924201 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBP36_HUMAN (7-516): 6.17e-126: 396: 35.31
+	Mm
		476838 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP7_MOUSE (6-500): 6.63e-101: 329: 18.97
+	Mm
		476893 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP47_MOUSE (4-483): 1.52e-99: 329: 17.63
+	Mm
		476741 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP46_MOUSE (79-376): 6.54e-100: 307: 25.75
+	Mm
		476939 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP3_MOUSE (66-375): 7.33e-25: 109: 27.17