HitPredict

Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 354 Hs			1 894
+	Hs
		475932 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		EPHA4_HUMAN (2-836): 0: 645: 19.10
+	Hs
		618497 GNAT2_HUMAN (1-354): 3.72e-167: 471: 69.49		EPHA4_HUMAN (2-836): 0: 645: 19.10
+	Hs
		618446 GNAZ_HUMAN (1-353): 7.69e-156: 443: 67.23		EPHA4_HUMAN (2-836): 0: 645: 19.10
+	Hs
		932071 GNA13_HUMAN (2-353): 2.06e-152: 435: 38.33		EPHA4_HUMAN (2-836): 0: 645: 19.10
+	Rn
		475872 GNAI3_RAT (1-354): 4.49e-175: 491: 98.59		INSR_RAT (276-851): 3.1e-134: 436: 27.83
+	Hs
		541428 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		FGFR1_HUMAN (505-815): 6.73e-56: 209: 40.12
+	Mm
		591100 GNAQ_MOUSE (1-353): 7.97e-162: 458: 51.41		MET_MOUSE (536-799): 5.49e-66: 243: 45.90
+	Mm
		267011 GNAZ_MOUSE (1-353): 2.49e-156: 444: 66.95		MET_MOUSE (536-799): 5.49e-66: 243: 45.90
+	Hs
		465478 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		IGF1R_HUMAN (234-385): 4.84e-12: 72.4: 18.07
+	Hs
		475956 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		TYRO3_HUMAN (2-328): 2.8e-14: 79.4: 14.82