HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP30 (Q70CQ3)
Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30)
Gene: USP30

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	29576527, 25527291, 28945247, 34129829, 32484330
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 517
+	Hs
		476213 UBC_HUMAN (1-685): 0: 846: 100.00		UBP47_HUMAN (62-504): 3.21e-76: 263: 15.95
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (13-429): 2.3e-81: 262: 15.49
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (27-429): 1.17e-79: 260: 16.09
+	Hs
		475523 UBC_HUMAN (1-685): 0: 846: 100.00		UBP14_HUMAN (9-512): 3.19e-73: 242: 16.35
+	Hs
		476624 UBC_HUMAN (1-685): 0: 846: 100.00		UBP15_HUMAN (59-262): 7.77e-44: 168: 23.90
+	Hs
		475693 UBC_HUMAN (1-685): 0: 846: 100.00		UBP4_HUMAN (65-261): 2.86e-41: 160: 24.75
+	Hs
		475403 UBC_HUMAN (1-685): 0: 846: 100.00		UBP6_HUMAN (69-260): 2.17e-40: 158: 25.91
+	Hs
		475502 UBC_HUMAN (1-685): 0: 846: 100.00		UBP11_HUMAN (46-261): 8.28e-40: 156: 22.83
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (330-507): 4.88e-28: 119: 16.29
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (238-509): 3.19e-25: 110: 13.87
+	Hs
		476545 UBC_HUMAN (1-685): 0: 846: 100.00		UBP21_HUMAN (344-507): 1.81e-24: 108: 13.42
+	Hs
		475440 UBC_HUMAN (1-685): 0: 846: 100.00		UBP8_HUMAN (346-511): 1.42e-22: 104: 15.66
+	Hs
		476400 UBC_HUMAN (1-685): 0: 846: 100.00		UBP42_HUMAN (351-502): 3.17e-22: 103: 18.18
+	Hs
		476493 UBC_HUMAN (1-685): 0: 846: 100.00		UBP36_HUMAN (351-502): 3.35e-21: 99: 16.99
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (350-503): 2.46e-15: 79.5: 17.26
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (350-502): 1.3e-13: 74.1: 17.37
+	Hs
		476067 UBC_HUMAN (1-685): 0: 846: 100.00		UBP32_HUMAN (252-346): 8.07e-10: 63.8: 26.32
+	Dr
		57752 F1QHN6_DANRE (229-685): 0: 555: 99.78		UBP30_DANRE (12-503): 5.52e-110: 337: 56.77
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (346-501): 1.28e-22: 103: 19.23
+	At
		1210478 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP27_ARATH (64-502): 3.31e-83: 268: 24.84