HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	12006492, 35120596, 19542561, 15053872, 11916981, 26456826, 28190767, 38803224
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	UEV~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0010008 - endosome membrane GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 390
+	Hs
		476026 UBC_HUMAN (1-685): 0: 846: 100.00		UEVLD_HUMAN (8-150): 2.58e-66: 219: 53.85
+	Sc
		477158 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		STP22_YEAST (21-380): 2.5e-106: 319: 20.65
+	Mm
		476825 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TS101_MOUSE (1-390): 0: 529: 94.63
+	Hs
		475159 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		TS101_HUMAN (1-390): 0: 528: 100.00
+	Hs
		398028 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		UEVLD_HUMAN (8-150): 2.58e-66: 219: 53.85