HitPredict

Interactor 1: A0AQH0 (A0AQH0)
Proteasome subunit beta
Gene: Prosbeta1

Interactor 2: TERA (Q7KN62)
Transitional endoplasmic reticulum ATPase TER94 (EC 3.6.4.6) (Valosin-containing protein homolog)
Gene: TER94

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 224 Dm			1 801
+	Dm
		1267908 PSA5_DROME (4-212): 6.35e-73: 223: 17.20		TERA_DROME (1-801): 0: 764: 100.00
+	Dm
		1264651 Q7K148_DROME (1-199): 4.85e-72: 222: 26.50		TERA_DROME (1-801): 0: 764: 100.00
+	Sc
		668367 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		CDC48_YEAST (1-801): 0: 733: 66.67
+	Sc
		679630 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		CDC48_YEAST (1-801): 0: 733: 66.67
+	Zm
		32605 B4FJY5_MAIZE (13-216): 7.81e-72: 221: 28.92		A0A1D6KUI9_MAIZE (3-801): 0: 746: 74.34
+	Hs
		701125 PSB5_HUMAN (11-219): 9.7e-73: 223: 27.14		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		700593 PSA5_HUMAN (4-211): 8.93e-73: 222: 15.60		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		165300 PSA7_HUMAN (4-214): 4.86e-72: 221: 15.60		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		681608 PSA4_HUMAN (4-214): 6.48e-72: 221: 13.76		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		934362 PSA6_HUMAN (4-218): 6.46e-72: 220: 17.49		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		701007 PSB6_HUMAN (3-219): 1.02e-71: 219: 56.68		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		700686 PSA5_HUMAN (4-211): 8.93e-73: 222: 15.60		AFG2A_HUMAN (412-748): 1.66e-68: 245: 29.91