Protein: PSB2
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit PUP1) (Multicatalytic endopeptidase complex subunit PUP1) (Proteasome component PUP1) (Proteinase YSCE subunit PUP1)

Gene: PSB2, PUP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P25043

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0004175 - endopeptidase activity
GO:0004298 - threonine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645127

PSB4
Proteasome subunit beta type-4

10

20

Small-scale

0.966

High

661454

PSA2
Proteasome subunit alpha type-2

7

20

Small-scale

0.961

High

668365

PSB3
Proteasome subunit beta type-3

7

20

Small-scale

0.956

High

668369

PSB5
Proteasome subunit beta type-5

7

20

Small-scale

0.952

High

668370

PSB7
Proteasome subunit beta type-7

6

20

Small-scale

0.929

High

668383

PSB1
Proteasome subunit beta type-1

5

20

Small-scale

0.918

High

668381

UMP1
Proteasome maturation factor UMP1

5

2

Small-scale

0.912

High

661372

PSA3
Proteasome subunit alpha type-3

4

20

Small-scale

0.881

High

636542

PSA7
Probable proteasome subunit alpha type-7

3

20

Small-scale

0.839

High

662016

PSB6
Proteasome subunit beta type-6

3

20

High-throughput

0.839

High

636628

PSA1
Proteasome subunit alpha type-1

2

20

High-throughput

0.776

High

668371

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.776

High

668394

PSA6
Proteasome subunit alpha type-6

2

20

High-throughput

0.776

High

668395

PSA4
Proteasome subunit alpha type-4

2

20

High-throughput

0.776

High

668378

PRS7
26S proteasome regulatory subunit 7 homolog

2

20

Small-scale

0.754

High

668404

PRS8
26S proteasome regulatory subunit 8 homolog

2

20

Small-scale

0.754

High

668419

RPN5
26S proteasome regulatory subunit RPN5

2

20

Small-scale

0.754

High

668398

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

11

20

Small-scale

0.750

High

668397

BLM10
Proteasome activator BLM10

2

10

Small-scale

0.727

High

668415

RPN8
26S proteasome regulatory subunit RPN8

3

20

Small-scale

0.640

High

668418

POC4
Proteasome chaperone 4

1

0

Small-scale

0.631

High

668367

CDC48
Cell division control protein 48

1

11

High-throughput

0.618

High

668376

PRS6A
26S proteasome regulatory subunit 6A

1

20

High-throughput

0.618

High

668377

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

668396

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

668402

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

668421

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

668375

RAD23
UV excision repair protein RAD23

2

20

Small-scale

0.601

High

668414

POC3
Proteasome chaperone 3

1

0

Small-scale

0.586

High

668372

RPN12
26S proteasome regulatory subunit RPN12

2

5

Small-scale

0.584

High

668380

POC2
Proteasome assembly chaperone 2

2

2

Small-scale

0.584

High

668387

RPN10
26S proteasome regulatory subunit RPN10

2

10

Small-scale

0.584

High

668390

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

3

Small-scale

0.555

High

668366

FUB1
Silencing boundary-establishment protein FUB1

1

2

High-throughput

0.553

High

668410

POC1
Proteasome chaperone 1

1

2

High-throughput

0.553

High

660831

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

668401

MCM6
DNA replication licensing factor MCM6

1

3

High-throughput

0.515

High

668379

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.514

High

470105

SPS1
Sporulation-specific protein 1

1

4

Small-scale

0.481

High

150263

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.479

High

314845

SEM1
26S proteasome complex subunit SEM1

1

1

High-throughput

0.479

High

668364

SIS1
Protein SIS1

1

5

High-throughput

0.479

High

668368

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

668373

RPN2
26S proteasome regulatory subunit RPN2

1

20

High-throughput

0.479

High

668384

ECM29
Proteasome component ECM29

1

12

High-throughput

0.479

High

668385

RPN1
26S proteasome regulatory subunit RPN1

1

20

High-throughput

0.479

High

668392

RPN3
26S proteasome regulatory subunit RPN3

1

8

High-throughput

0.479

High

668399

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

12

High-throughput

0.479

High

668403

CDC14
Tyrosine-protein phosphatase CDC14

1

3

High-throughput

0.479

High

668407

RPN9
26S proteasome regulatory subunit RPN9

1

12

High-throughput

0.479

High

668408

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

668411

RPN7
26S proteasome regulatory subunit RPN7

1

20

High-throughput

0.479

High

668416

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

668374

SNQ2
Protein SNQ2

1

2

High-throughput

0.470

High

668406

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

668413

LUC7
Protein LUC7

1

0

High-throughput

0.458

High

543904

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

668386

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

668393

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

668412

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.445

High

668389

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.437

High

668391

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.407

High

668382

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.269

Low

668405

YD179
Uncharacterized protein YDR179W-A

1

0

High-throughput

0.269

Low

668400

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.251

Low

533489

TIR1
Cold shock-induced protein TIR1

1

0

High-throughput

0.249

Low

668388

AIM2
Protein AIM2

1

0

High-throughput

0.249

Low

668409

NCW2
Cell wall biogenesis protein NCW2

1

0

High-throughput

0.249

Low

668417

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

668420

SVS1
Protein SVS1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025