Protein: PSB1
Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit PRE3) (Multicatalytic endopeptidase complex subunit PRE3) (Proteasome component PRE3) (Proteinase YSCE subunit PRE3)

Gene: PSB1, PRE3
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P38624

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0004175 - endopeptidase activity
GO:0004298 - threonine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645163

PSB4
Proteasome subunit beta type-4

13

20

Small-scale

0.978

High

721254

PSB5
Proteasome subunit beta type-5

8

20

Small-scale

0.966

High

721303

PSB7
Proteasome subunit beta type-7

7

20

Small-scale

0.954

High

636656

PSA1
Proteasome subunit alpha type-1

5

20

High-throughput

0.922

High

636570

PSA7
Probable proteasome subunit alpha type-7

5

20

Small-scale

0.919

High

668383

PSB2
Proteasome subunit beta type-2

5

20

Small-scale

0.918

High

800867

RPN5
26S proteasome regulatory subunit RPN5

4

20

Small-scale

0.892

High

661508

PSA2
Proteasome subunit alpha type-2

4

20

High-throughput

0.887

High

662037

PSB6
Proteasome subunit beta type-6

3

19

High-throughput

0.855

High

800847

PSA4
Proteasome subunit alpha type-4

3

20

High-throughput

0.855

High

800846

PSA6
Proteasome subunit alpha type-6

3

20

Small-scale

0.849

High

750933

PRS7
26S proteasome regulatory subunit 7 homolog

3

20

Small-scale

0.847

High

800851

BLM10
Proteasome activator BLM10

3

13

Small-scale

0.840

High

675243

PSB3
Proteasome subunit beta type-3

3

20

Small-scale

0.839

High

750642

PRS6A
26S proteasome regulatory subunit 6A

3

20

Small-scale

0.827

High

797524

UMP1
Proteasome maturation factor UMP1

3

3

Small-scale

0.827

High

661403

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.776

High

735924

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.776

High

800852

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.747

High

800839

ECM29
Proteasome component ECM29

3

16

High-throughput

0.656

High

679630

CDC48
Cell division control protein 48

1

12

High-throughput

0.618

High

750833

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

800838

PSB1
Proteasome subunit beta type-1

1

19

High-throughput

0.618

High

800848

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

800854

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

800857

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

800869

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

740152

RPN2
26S proteasome regulatory subunit RPN2

2

20

High-throughput

0.611

High

800840

RPN1
26S proteasome regulatory subunit RPN1

2

20

High-throughput

0.611

High

800844

RPN3
26S proteasome regulatory subunit RPN3

2

11

High-throughput

0.611

High

800863

RHC31
DNA damage tolerance protein RHC31

2

3

Small-scale

0.608

High

679044

FUB1
Silencing boundary-establishment protein FUB1

1

3

High-throughput

0.553

High

800861

POC1
Proteasome chaperone 1

1

3

High-throughput

0.553

High

800850

SMK1
Sporulation-specific mitogen-activated protein kinase SMK1

1

5

High-throughput

0.536

High

800856

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

4

Small-scale

0.481

High

150281

RPN13
26S proteasome regulatory subunit RPN13

1

2

High-throughput

0.479

High

314866

SEM1
26S proteasome complex subunit SEM1

1

2

High-throughput

0.479

High

579313

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

603049

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

670648

SIS1
Protein SIS1

1

7

High-throughput

0.479

High

706975

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

738299

RPN12
26S proteasome regulatory subunit RPN12

1

6

High-throughput

0.479

High

779988

POC2
Proteasome assembly chaperone 2

1

3

High-throughput

0.479

High

795317

ATG8
Autophagy-related protein 8

1

7

High-throughput

0.479

High

800841

RPN10
26S proteasome regulatory subunit RPN10

1

15

High-throughput

0.479

High

800853

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

16

High-throughput

0.479

High

800858

TOM1
E3 ubiquitin-protein ligase TOM1

1

12

High-throughput

0.479

High

800859

RPN9
26S proteasome regulatory subunit RPN9

1

16

High-throughput

0.479

High

800860

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

800862

RPN7
26S proteasome regulatory subunit RPN7

1

20

High-throughput

0.479

High

800866

RPN8
26S proteasome regulatory subunit RPN8

1

20

High-throughput

0.479

High

553536

PDR1
Transcription factor PDR1

1

0

High-throughput

0.458

High

753019

SPC29
Spindle pole component 29

1

0

High-throughput

0.458

High

800855

CAF40
Protein CAF40

1

0

High-throughput

0.458

High

800845

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

682263

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

800843

ATC3
Phospholipid-transporting ATPase DRS2

1

4

High-throughput

0.437

High

800849

MLP2
Protein MLP2

1

5

High-throughput

0.437

High

800865

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.437

High

800842

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.407

High

800864

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.265

Low

746062

SEC6
Exocyst complex component SEC6

1

0

High-throughput

0.249

Low

800868

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025