HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: MAP1B (P46821)
Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]
Gene: MAP1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	31694235
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031175 - neuron projection development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 2468
+	Hs
		861057 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MAP1B_HUMAN (1-2468): 0: 941: 100.00
+	Hs
		481414 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		SRRM2_HUMAN (974-2359): 3.62e-17: 91.3: 10.57
+	Hs
		481343 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		TITIN_HUMAN (381-1131): 3.06e-10: 68.7: 8.39
+	Hs
		1065251 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		ANR11_HUMAN (558-2379): 2.06e-20: 102: 10.44
+	Hs
		1065500 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		SRRM2_HUMAN (974-2359): 3.62e-17: 91.3: 10.57
+	Hs
		1413243 SOX7_HUMAN (65-181): 1.31e-28: 112: 19.66		NCOR2_HUMAN (436-2401): 3.73e-13: 77.9: 8.73
+	Hs
		334321 HM20B_HUMAN (64-165): 1.23e-15: 76: 32.35		TACC2_HUMAN (362-2393): 6.23e-23: 110: 9.19
+	Mm
		107246 Q60I23_MOUSE (3-94): 1.01e-24: 100: 23.91		F8VQL9_MOUSE (822-2440): 1.06e-14: 82.9: 8.77
+	Hs
		1065378 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		CIC_HUMAN (404-1143): 1.31e-09: 66.4: 8.11
+	Hs
		872949 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		NCOR2_HUMAN (436-2401): 3.73e-13: 77.9: 8.73
+	Hs
		872193 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MAP1A_HUMAN (355-1255): 2.89e-12: 75.2: 9.10
+	Hs
		1434988 SOX17_HUMAN (7-90): 3.94e-22: 94.8: 19.05		NCOR2_HUMAN (436-2401): 3.73e-13: 77.9: 8.73
+	Hs
		942132 SOX10_HUMAN (4-98): 2.08e-21: 93.2: 14.74		NCOR2_HUMAN (436-2401): 3.73e-13: 77.9: 8.73
+	Hs
		872653 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		CIC_HUMAN (404-1143): 1.31e-09: 66.4: 8.11
+	Hs
		872662 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MINT_HUMAN (361-1474): 6.79e-09: 64: 6.91
+	Hs
		1401392 SOX17_HUMAN (7-90): 3.94e-22: 94.8: 19.05		CIC_HUMAN (404-1143): 1.31e-09: 66.4: 8.11
+	Hs
		942121 SOX10_HUMAN (4-98): 2.08e-21: 93.2: 14.74		CIC_HUMAN (404-1143): 1.31e-09: 66.4: 8.11
+	Hs
		551603 UBF1_HUMAN (10-158): 4.17e-09: 57.8: 23.60		NFH_HUMAN (605-1346): 2.67e-10: 68.1: 14.91
+	Hs
		1024148 TFAM_HUMAN (95-186): 2.96e-09: 57.1: 17.39		CIC_HUMAN (404-1143): 1.31e-09: 66.4: 8.11