HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16469706, 27992601
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008270 - zinc ion binding and 1 others more... GO:0060090 - molecular adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 693
+	Hs
		487803 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD7_HUMAN (18-590): 1.32e-19: 96.3: 11.81
+	Hs
		487246 ANDR_HUMAN (1-920): 0: 966: 100.00		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		487596 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2C_HUMAN (103-538): 1.38e-09: 63.9: 14.25
+	Hs
		487538 ANDR_HUMAN (1-920): 0: 966: 100.00		SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69
+	Hs
		487247 ANDR_HUMAN (1-920): 0: 966: 100.00		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		370578 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		377742 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		370000 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		369455 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		377445 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		370607 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CHD7_HUMAN (18-590): 1.32e-19: 96.3: 11.81
+	Hs
		368927 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Hs
		369213 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		257541 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		370040 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2C_HUMAN (103-538): 1.38e-09: 63.9: 14.25
+	Hs
		369214 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		377191 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		257543 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		377716 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SC31B_HUMAN (139-489): 1.57e-09: 63.5: 9.52
+	Hs
		377192 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81