HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030667 - secretory granule membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 193
+	Hs
		382373 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		382382 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		382270 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		382389 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		382371 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		382288 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		382370 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		382381 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120272 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		354401 HLAB_HUMAN (1-363): 6.17e-157: 446: 85.40		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		488185 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436130 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		488180 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		488115 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		488178 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		570315 HLAG_HUMAN (1-339): 2.59e-152: 434: 79.35		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		488184 HLAC_HUMAN (1-366): 8.9e-155: 441: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94