HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	27383765
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:1900034 - regulation of cellular response to heat
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 2442
+	Hs
		1056910 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		152675 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1170076 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		496924 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		653964 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998710 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		554303 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998826 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		497252 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (1984-2407): 1.04e-11: 73.3: 10.86
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (2056-2438): 1.42e-10: 69.4: 9.60
+	Hs
		654076 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		1057027 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		1056838 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		631425 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		170402 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (244-1120): 3.23e-21: 104: 9.85
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (1947-2441): 7.35e-18: 93.3: 11.02
+	Mm
		1207212 NCOA6_MOUSE (23-739): 1.31e-24: 112: 9.76		KMT2C_MOUSE (1733-2440): 7.05e-13: 77.1: 11.27
+	Hs
		152667 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89