HitPredict

Interactor 1: H2AZ (P0C0S6)
Histone H2A.Z (H2A/z)
Gene: H2az1

Interactor 2: SMCA4 (Q3TKT4)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)
Gene: Smarca4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	23260146
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~SnAC, Histone~SNF2-rel_dom
Common GO terms	GO:0000791 - euchromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Mm			1 1613
+	Hs
		501937 H2AZ_HUMAN (1-128): 9.84e-62: 186: 100.00		SMCA4_HUMAN (1-1613): 0: 1064: 97.21
+	Hs
		243517 H2AZ_HUMAN (1-128): 9.84e-62: 186: 100.00		SMCA5_HUMAN (595-1604): 0: 774: 27.31
+	Hs
		501917 H2AZ_HUMAN (1-128): 9.84e-62: 186: 100.00		SMCA1_HUMAN (626-1604): 0: 769: 29.23
+	Hs
		243671 H2A2B_HUMAN (5-127): 9.24e-56: 171: 59.68		SMCA5_HUMAN (595-1604): 0: 774: 27.31
+	Hs
		243509 H2A1B_HUMAN (5-125): 9.22e-55: 169: 61.48		SMCA5_HUMAN (595-1604): 0: 774: 27.31
+	Hs
		243527 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA5_HUMAN (595-1604): 0: 774: 27.31
+	Hs
		591490 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA1_HUMAN (626-1604): 0: 769: 29.23
+	Hs
		501987 H2AZ_HUMAN (1-128): 9.84e-62: 186: 100.00		CHD4_HUMAN (404-1613): 0: 710: 21.96
+	Hs
		502139 H2AZ_HUMAN (1-128): 9.84e-62: 186: 100.00		CHD8_HUMAN (10-1482): 0: 709: 20.76
+	Hs
		1088507 H2A1H_HUMAN (5-125): 2.99e-55: 170: 61.48		CHD3_HUMAN (258-1612): 0: 718: 21.61
+	Hs
		418961 H2A1B_HUMAN (5-125): 9.22e-55: 169: 61.48		CHD3_HUMAN (258-1612): 0: 718: 21.61
+	Hs
		1132809 H2A2B_HUMAN (5-127): 9.24e-56: 171: 59.68		CHD4_HUMAN (404-1613): 0: 710: 21.96
+	Hs
		1132728 H2A2C_HUMAN (5-127): 3.48e-55: 170: 61.29		CHD4_HUMAN (404-1613): 0: 710: 21.96
+	Hs
		1132896 H2A1H_HUMAN (5-125): 2.99e-55: 170: 61.48		CHD4_HUMAN (404-1613): 0: 710: 21.96
+	Hs
		418990 H2A1B_HUMAN (5-125): 9.22e-55: 169: 61.48		CHD4_HUMAN (404-1613): 0: 710: 21.96
+	Hs
		419217 H2A1B_HUMAN (5-125): 9.22e-55: 169: 61.48		CHD8_HUMAN (10-1482): 0: 709: 20.76
+	Hs
		502043 H2AZ_HUMAN (1-128): 9.84e-62: 186: 100.00		CHD1L_HUMAN (741-1474): 0: 692: 33.59
+	Hs
		419014 H2A1B_HUMAN (5-125): 9.22e-55: 169: 61.48		CHD9_HUMAN (46-1411): 0: 704: 21.81
+	Hs
		1272802 H2A3_HUMAN (5-125): 5.1e-55: 169: 62.30		CHD1L_HUMAN (741-1474): 0: 692: 33.59
+	Hs
		160158 H2A1B_HUMAN (5-125): 9.22e-55: 169: 61.48		CHD2_HUMAN (343-1439): 0: 668: 27.02