HitPredict

Interactor 1: RAB3A (P20336)
Ras-related protein Rab-3A
Gene: RAB3A

Interactor 2: RB33B (Q9H082)
Ras-related protein Rab-33B
Gene: RAB33B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005768 - endosome GO:0017157 - regulation of exocytosis GO:0098793 - presynapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 220 Hs			1 229
+	Mm
		877190 RAB3C_MOUSE (1-220): 1.29e-95: 280: 83.18		RAB8A_MOUSE (26-226): 2.83e-87: 258: 38.54
+	Mm
		919023 RAB3C_MOUSE (1-220): 1.29e-95: 280: 83.18		RAB1B_MOUSE (26-229): 1.17e-85: 254: 38.35
+	Zm
		73944 B4FAE1_MAIZE (15-219): 1.85e-91: 268: 45.85		B4FAE1_MAIZE (26-229): 6.15e-89: 262: 36.72
+	Hs
		591540 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62
+	Hs
		591537 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18
+	Hs
		918846 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62
+	Hs
		895026 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18
+	Hs
		918916 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69
+	Mm
		895573 RAB3C_MOUSE (1-220): 1.29e-95: 280: 83.18		RAB10_MOUSE (26-229): 1.81e-80: 240: 35.78
+	Hs
		918944 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAB1B_HUMAN (26-229): 8.1e-86: 254: 38.35
+	Mm
		919000 RAB1A_MOUSE (12-220): 2.68e-90: 265: 44.02		RAB1B_MOUSE (26-229): 1.17e-85: 254: 38.35
+	Hs
		1259991 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69
+	Hs
		895264 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18
+	Hs
		591536 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		RAB8A_HUMAN (26-226): 4.97e-80: 240: 37.56
+	Hs
		894715 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAB8A_HUMAN (26-226): 4.97e-80: 240: 37.56
+	Hs
		1273009 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAB8B_HUMAN (26-226): 3.5e-80: 240: 37.44
+	Hs
		895549 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAB10_HUMAN (26-229): 1.81e-80: 240: 35.78
+	Dm
		627449 RAB3_DROME (1-220): 9.14e-94: 275: 76.47		Q9W5X0_DROME (33-222): 1.12e-45: 152: 43.30
+	Hs
		59812 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		RAB19_HUMAN (33-221): 2.74e-46: 154: 41.89