HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin, Histone_H2A_C~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 156
+	Hs
		418929 H2A1B_HUMAN (1-130): 1.37e-66: 199: 98.46		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		987073 H2A2A_HUMAN (1-130): 8.46e-67: 199: 98.46		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		987089 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		987098 H2A2B_HUMAN (1-130): 2.56e-65: 195: 94.62		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		591587 H2AX_HUMAN (1-130): 6.66e-63: 190: 88.81		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		418930 H2A1B_HUMAN (1-130): 1.37e-66: 199: 98.46		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		502303 H2A1_HUMAN (1-130): 1.11e-66: 199: 100.00		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		987381 H2A2A_HUMAN (1-130): 8.46e-67: 199: 98.46		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		987394 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		987436 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		987449 H2A1H_HUMAN (1-128): 6.09e-66: 197: 100.00		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		987460 H2A1J_HUMAN (1-128): 3.89e-66: 197: 99.22		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Rn
		506193 H2A2A_RAT (1-130): 8.46e-67: 199: 98.46		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	Hs
		591588 H2AX_HUMAN (1-130): 6.66e-63: 190: 88.81		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		507067 H2AX_HUMAN (1-130): 6.66e-63: 190: 88.81		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	At
		1168034 H2A6_ARATH (1-128): 7.47e-59: 179: 71.32		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Sc
		419555 H2A2_YEAST (16-127): 4.06e-53: 165: 81.25		RL40A_YEAST (1-125): 2.08e-42: 139: 64.00
+	Dm
		1014848 H2A_DROME (17-125): 5.23e-59: 179: 89.91		R9PY16_DROME (1-68): 7.14e-29: 108: 91.18