HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: H2A3 (Q7L7L0)
Histone H2A type 3 (H2A-clustered histone 25)
Gene: H2AC25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin, Histone_H2A_C~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 130
+	Hs
		418929 RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00		H2A1B_HUMAN (1-130): 7.83e-68: 202: 99.23
+	Hs
		502302 RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00		H2A1_HUMAN (1-130): 6.57e-68: 202: 97.69
+	Hs
		987073 RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00		H2A2A_HUMAN (1-130): 5.05e-68: 202: 97.69
+	Hs
		987098 RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00		H2A2B_HUMAN (1-130): 1.95e-66: 198: 94.62
+	Hs
		591587 RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00		H2AX_HUMAN (1-130): 7.61e-64: 192: 88.81
+	Hs
		418930 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A1B_HUMAN (1-130): 7.83e-68: 202: 99.23
+	Hs
		502303 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A1_HUMAN (1-130): 6.57e-68: 202: 97.69
+	Hs
		987381 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A2A_HUMAN (1-130): 5.05e-68: 202: 97.69
+	Hs
		987394 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A3_HUMAN (1-130): 5.58e-68: 202: 100.00
+	Hs
		987436 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A1C_HUMAN (1-130): 5.28e-68: 202: 99.23
+	Hs
		987460 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A1J_HUMAN (1-128): 2.65e-67: 201: 96.88
+	Hs
		987449 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2A1H_HUMAN (1-128): 4.11e-67: 200: 97.66
+	Rn
		506193 UBC_RAT (1-119): 1.58e-36: 134: 68.29		H2A2A_RAT (1-130): 5.05e-68: 202: 97.69
+	Hs
		591588 RL40_HUMAN (1-125): 5.35e-44: 142: 64.80		H2AX_HUMAN (1-130): 7.61e-64: 192: 88.81
+	Hs
		507067 UBB_HUMAN (1-76): 6.68e-36: 125: 100.00		H2AX_HUMAN (1-130): 7.61e-64: 192: 88.81
+	At
		1168034 UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81		H2A6_ARATH (1-128): 9.84e-60: 181: 71.32
+	Sc
		419555 RL40A_YEAST (1-125): 2.08e-42: 139: 64.00		H2A2_YEAST (16-127): 4.89e-53: 164: 81.25
+	Dm
		1014848 R9PY16_DROME (1-68): 7.14e-29: 108: 91.18		H2A_DROME (17-125): 7.52e-60: 181: 89.91