HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: FXL15 (Q9H469)
F-box/LRR-repeat protein 15 (F-box only protein 37)
Gene: FBXL15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 300
+	Hs
		483805 HS71B_HUMAN (1-646): 0: 948: 84.37		FXL15_HUMAN (1-300): 3.34e-68: 215: 100.00
+	Hs
		871783 HSP72_HUMAN (2-646): 0: 940: 85.47		FXL15_HUMAN (1-300): 3.34e-68: 215: 100.00
+	Hs
		1031212 Q53FC7_HUMAN (6-646): 0: 951: 77.07		SKP2_HUMAN (5-293): 1.21e-37: 139: 18.63
+	Zm
		30990 A0A1D6KE29_MAIZE (4-646): 0: 951: 76.32		B4G0W0_MAIZE (3-282): 7.81e-37: 135: 19.39
+	Hs
		504929 HSP7C_HUMAN (1-646): 0: 967: 100.00		FBXL4_HUMAN (17-276): 1.38e-29: 119: 21.40
+	Hs
		871824 HSP72_HUMAN (2-646): 0: 940: 85.47		FBXL4_HUMAN (17-276): 1.38e-29: 119: 21.40
+	Hs
		504393 HSP7C_HUMAN (1-646): 0: 967: 100.00		FXL16_HUMAN (37-195): 2.77e-11: 65.7: 18.58
+	Mm
		926140 HSP7C_MOUSE (1-646): 0: 967: 99.85		KDM2B_MOUSE (1-166): 1.59e-10: 63.8: 16.83