HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBE2Z (Q9H832)
Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
Gene: UBE2Z

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27182664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 354
+	Hs
		508684 UBC_HUMAN (1-685): 0: 857: 100.00		BIRC6_HUMAN (87-353): 1.3e-68: 235: 29.62
+	Hs
		508868 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D4_HUMAN (99-253): 4.06e-73: 225: 33.12
+	Hs
		507793 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D2_HUMAN (99-253): 1.2e-72: 223: 34.40
+	Hs
		507701 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D1_HUMAN (99-253): 1e-71: 221: 31.85
+	Hs
		507755 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D3_HUMAN (99-253): 2.57e-71: 220: 34.40
+	Hs
		508388 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E3_HUMAN (74-253): 3.27e-65: 207: 27.47
+	Hs
		508456 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E2_HUMAN (44-253): 1.95e-65: 207: 24.53
+	Hs
		507705 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E1_HUMAN (82-253): 3.39e-65: 206: 27.01
+	Hs
		508677 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2T_HUMAN (99-291): 5.64e-62: 198: 27.14
+	Hs
		507678 UBC_HUMAN (1-685): 0: 857: 100.00		UB2R1_HUMAN (96-283): 8.42e-57: 186: 26.36
+	Rn
		92896 UBC_RAT (1-637): 0: 779: 98.90		UB2D1_RAT (99-253): 1e-71: 221: 31.85
+	Xl
		982387 Q7SY79_XENLA (77-685): 0: 752: 99.84		UB2D2_XENLA (99-253): 1.2e-72: 223: 34.40
+	Hs
		508578 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2O_HUMAN (104-242): 7.09e-21: 96.3: 40.14
+	Hs
		507757 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2N_HUMAN (103-226): 3.79e-18: 82: 36.29
+	Dm
		683066 Q9W418_DROME (229-685): 0: 567: 99.78		UBCD1_DROME (99-253): 2.8e-71: 220: 34.40
+	Sc
		509374 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC4_YEAST (99-253): 1.81e-68: 213: 31.85
+	At
		762746 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC8_ARATH (99-253): 3.4e-69: 215: 35.67
+	At
		762762 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC9_ARATH (99-253): 4.56e-69: 214: 36.31
+	At
		762777 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC10_ARATH (99-253): 1.05e-68: 213: 35.67
+	At
		762787 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC11_ARATH (99-253): 3.01e-68: 212: 35.03