HitPredict

Interactor 1: PKHG3 (A1L390)
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)
Gene: PLEKHG3

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	36931259, 28514442, unassigned3799
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1219 Hs			1 246
+	Hs
		51063 PKHG3_HUMAN (1-1219): 0: 963: 100.00		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		51068 PKHG3_HUMAN (1-1219): 0: 963: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		51042 PKHG3_HUMAN (1-1219): 0: 963: 100.00		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		51061 PKHG3_HUMAN (1-1219): 0: 963: 100.00		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		51073 PKHG3_HUMAN (1-1219): 0: 963: 100.00		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		51047 PKHG3_HUMAN (1-1219): 0: 963: 100.00		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62
+	Hs
		967010 PKHG1_HUMAN (45-917): 2.21e-144: 473: 35.85		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		1049899 PKHG1_HUMAN (45-917): 2.21e-144: 473: 35.85		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		971770 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		730045 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Hs
		990486 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		971851 ARHG2_HUMAN (12-801): 4.35e-107: 362: 12.63		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		730123 ARHG2_HUMAN (12-801): 4.35e-107: 362: 12.63		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Hs
		691234 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		691311 ARHG2_HUMAN (12-801): 4.35e-107: 362: 12.63		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		966601 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		1049547 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		966706 ARHG2_HUMAN (12-801): 4.35e-107: 362: 12.63		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		730758 ARG28_HUMAN (2-891): 5.33e-108: 376: 12.87		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62
+	Hs
		730813 ARHG2_HUMAN (12-801): 4.35e-107: 362: 12.63		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62