HitPredict

Interactor 1: RL1A (P0CX43)
Large ribosomal subunit protein uL1A (60S ribosomal protein L1-A) (L10a)
Gene: RPL1A

Interactor 2: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	16429126, 21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~Ribosomal_L1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 217 Sc			1 606
+	Hs
		985359 RL10A_HUMAN (2-217): 4.3e-79: 237: 59.72		DDX18_HUMAN (6-467): 5.11e-159: 472: 29.61
+	Sc
		513561 RL1A_YEAST (1-217): 1.85e-79: 238: 100.00		HAS1_YEAST (6-467): 2.43e-138: 414: 30.98
+	Hs
		301236 RL1D1_HUMAN (3-217): 7.28e-53: 178: 21.01		DDX18_HUMAN (6-467): 5.11e-159: 472: 29.61
+	Sc
		682378 RM01_YEAST (9-216): 2.04e-37: 133: 14.35		SPB4_YEAST (1-606): 7.37e-148: 442: 100.00
+	Dm
		1471252 Y3096_DROME (69-217): 1.55e-26: 108: 21.38		DDX18_DROME (6-481): 5.9e-153: 457: 28.96
+	Sc
		682270 CIC1_YEAST (59-217): 6.52e-22: 94: 15.70		SPB4_YEAST (1-606): 7.37e-148: 442: 100.00
+	Sc
		803922 CIC1_YEAST (59-217): 6.52e-22: 94: 15.70		HAS1_YEAST (6-467): 2.43e-138: 414: 30.98
+	Sc
		666449 CIC1_YEAST (59-217): 6.52e-22: 94: 15.70		DBP2_YEAST (2-402): 2.16e-123: 376: 25.43
+	Hs
		985150 RL10A_HUMAN (2-217): 4.3e-79: 237: 59.72		DDX10_HUMAN (21-472): 5.25e-47: 179: 29.67
+	Ec
		492699 RL1_ECOLI (2-216): 2.27e-46: 154: 19.28		DEAD_ECOLI (18-393): 1.02e-48: 181: 32.99
+	Sc
		632658 RL1D1_YEAST (4-217): 9.09e-38: 134: 14.46		DBP4_YEAST (21-467): 7.03e-51: 189: 31.36
+	Sc
		746622 CIC1_YEAST (59-217): 6.52e-22: 94: 15.70		DRS1_YEAST (21-392): 3.92e-47: 178: 31.75